Iván Omar Romero Estudillo
Doctorado en Ciencias (Química) Universidad de La Laguna, Instituto de Productos Naturales y Agrobiología del Consejo Superior de Investigaciones Cientifícas. (Tenerife, España), 2014
Profesor: Investigador Cátedra-CONACYT
SNI: II
Líneas de Investigación: Síntesis y evaluación biológica de nuevos compuestos con actividad biológica.
Laboratorio de Síntesis de compuestos orgánicos de interés farmacéutico
Cuerpo Académico: Síntesis Orgánica
ivan.romeroest@uaem.mx | Teléfono: +52 777 329 7997 Ext. 6007
ORCID: 0000-0003-3924-3598 |Scopus Author ID: 41862207400 |
2022
25. Ordónez, M.*, Argüello-Velasco, R. O., Romero-Estudillo, I., Labastida-Galván, V., & Miranda-Blancas, T. (2023). First stereoselective synthesis of diethyl cis- and trans-(4-hydroxy-1,2,3,4-tetrahydroquinolin-2-yl) phosphonates and ethyl phenylphosphinates from quinolin-4(1H)-one. Synthesis. DOI: 10.1055/a-2164-2075
24. Rodríguez-Mejía, L. C.; Romero-Estudillo, I.; Rivillas-Acevedo, L. A.; French-Pacheco, L.; Silva-Martínez, G. A.; Alvarado-Caudillo, Y.; Colín-Castelán, D.; Rodríguez-Ríos, D.; Wrobel, K.; Wrobel, K.; Lund, G.; Zaina, S*. The DNA Methyltransferase Inhibitor RG108 Is Converted to Activator Following Conjugation with Short Peptides. Int. J. Pept. Res. Ther. 2022, 28 (3), 79. DOI: 10.1007/s10989-022-10390-5.
23. Romero-Estrada, A.; Boto, A.; González-Christen, J.; Romero-Estudillo, I.; Garduño-Ramírez, M. L.; Razo-Hernández, R. S.; Marquina, S.; Maldonado-Magaña, A.; Columba-Palomares, M. C.; Sánchez-Carranza, J. N.; Alvarez, L.* Synthesis, Biological Evaluation, and Molecular Docking Study of 3-Amino and 3-Hydroxy- Seco A Derivatives of α-Amyrin and 3-Epilupeol as Inhibitors of COX-2 Activity and NF-kB Activation. J. Nat. Prod. 2022, acs.jnatprod.1c00827. DOI: 10.1021/acs.jnatprod.1c00827
22. Argüello-Velasco, R. O.; Morales-Solís, J. C.; Muñoz-Vidales, M.; Viveros-Ceballos, J. L.; Romero-Estudillo, I.; Ordóñez, M*. An Efficient Synthesis of Cis-4-Hydroxyphosphonic and Cis-4-Hydroxyphosphinic Analogs of Pipecolic Acid from Cyclic Enaminones. Amino Acids 2022, 54 (2), DOI: 10.1007/s00726-022-03124-w.
2021
21. Boto, A*.; González, C*. C.; Hernández, D.; Romero-Estudillo, I.; Saavedra, C. J. Site-Selective
Modification of Peptide Backbones. Org. Chem. Front. 2021, 8 (23), 6720–6759. DOI:10.1039/D1QO00892G
2020
20. Cuevas, F.; Saavedra, C. J.; Romero‐Estudillo, I.*; Boto, A.*; Ordóñez, M.; Vergara, I. Structural Diversity Using Hyp “Customizable Units” : Proof‐of‐Concept Synthesis of Sansalvamide‐Related Antitumoral Peptides. European J. Org. Chem. 2021, 2021 (6), 933–943 DOI: 10.1002/ejoc.202001427
19. Saavedra Fernández, C. J., Cuevas, F., Romero-Estudillo, I., & Boto, A.* (2020). Synthesis of
Diketopiperazine Scaffolds with Tailored N‐ and α‐Chains by Selective Modification of Customizable
Units. Advanced Synthesis & Catalysis, adsc.202000470. https://doi.org/10.1002/adsc.202000470
ARTÍCULOS EN REVISTAS INDEXADAS
2020
21. Boto, A*.; González, C*. C.; Hernández, D.; Romero-Estudillo, I.; Saavedra, C. J. Site-Selective
Modification of Peptide Backbones. Org. Chem. Front. 2021, 8 (23), 6720–6759.
2020
20. Cuevas, F.; Saavedra, C. J.; Romero‐Estudillo, I.*; Boto, A.*; Ordóñez, M.; Vergara, I. Structural Diversity Using Hyp “Customizable Units” : Proof‐of‐Concept Synthesis of Sansalvamide‐Related Antitumoral Peptides. European J. Org. Chem. 2021, 2021 (6), 933–943 DOI: 10.1002/ejoc.202001427
19. Saavedra Fernández, C. J., Cuevas, F., Romero-Estudillo, I., & Boto, A.* (2020). Synthesis of Diketopiperazine Scaffolds with Tailored N‐ and α‐Chains by Selective Modification of Customizable Units. Advanced Synthesis & Catalysis, adsc.202000470. https://doi.org/10.1002/adsc.202000470
2019
18. Hernández-Moreno, J. T.; Romero-Estudillo, I.; Cativiela, C.; Ordóñez, M.* Practical Synthesis of 1,2,3,4-Tetrahydroisoquinoline-1-Phosphonic and -1-Phosphinic Acids through Kabachnik–Fields and Aza-Pudovik Reaction. Synthesis (Stuttg). 2019 DOI: 10.1055/s-0039-1690755
17. Romero-Estudillo, I.; Viveros-Ceballos, J. L.; Cazares-Carreño, O.; González-Morales, A.; de Jesús, B. F.; López-Castillo, M.; Razo-Hernández, R. S.; Castañeda-Corral, G.*; Ordóñez, M.* 000Synthesis of New α-Aminophosphonates: Evaluation as Anti-Inflammatory Agents and QSAR Studies. Bioorg. Med. Chem. 2019, 27 (12), 2376–2386. DOI: 10.1016/j.bmc.2018.12.041
16. Salgado-Escobar, O.; Hernández-Guadarrama, A.; Romero-Estudillo, I.; Linzaga-Elizalde, I.* Direct Synthesis of Phosphonates and α-Amino-Phosphonates from 1,3-Benzoxazines. Molecules 2019, 24 (2), 294. DOI: 10.3390/molecules24020294
2017
15. Boto, A.*; González, C.; Hernández, D.; Romero-Estudillo, I.; Rodriguez-Paz, N.; Lastra, J. M. P. de la. The Search for New Antimicrobial Agents, by Site-Selective Peptide Modification. Proceedings 2017, 1 (10), 673. DOI: 10.3390/proceedings1060673
14. Ordóñez, M.*; Viveros‐Ceballos, J. L.; Estudillo, I. R. Stereoselective Synthesis of α‐Aminophosphonic Acids through Pudovik and Kabachnik‐Fields Reaction. In Amino Acid - New Insights and Roles in Plant and Animal; InTech, 2017. DOI: 10.5772/intechopen.68707
2016
13. Boto, A.*; Romero-Estudillo, I.; Carro, C. Microwave versus Conventional Light Activation of O‐Radical Scission Processes. European J. Org. Chem. 2016. DOI: 10.1002/ejoc.201601034
12. Ordóñez, M.*; Cativiela, C.*; Romero-Estudillo, I. An Update on the Stereoselective Synthesis of γ-Amino Acids. Tetrahedron: Asymmetry 2016, 27 (20), 999–1055. DOI: 10.1016/j.tetasy.2016.08.011
11. Ramírez‐Marroquín, O. A.; Romero‐Estudillo, I.; Viveros‐Ceballos, J. L.; Cativiela, C.; Ordóñez, M.* Convenient Synthesis of Cyclic α‐Aminophosphonates by Alkylation–Cyclization Reaction of Iminophosphoglycinates Using Phase‐Transfer Catalysis. European J. Org. Chem. 2016, 2016 (2), 308–313. DOI: 10.1002/ejoc.201501203
2015
10. Romero-Estudillo, I.; Boto, A.* Domino Process Achieves Site-Selective Peptide Modification with High Optical Purity. Applications to Chain Diversification and Peptide Ligation. J. Org. Chem. 2015, 80 (19), 9379–9391. DOI: 10.1021/acs.joc.5b00932
9. Romero‐Estudillo, I.; Saavedra, C.; Boto, A.*; Álvarez, E. Site‐selective Modification of Peptides: From “customizable Units” to Novel Α‐aryl and Α‐alkyl Glycine Derivatives, and Components of Branched Peptides. Pept. Sci. 2015, 104 (5), 650–662. DOI: 10.1002/bip.22642
2014
8. Batchu, V. R.; Romero-Estudillo, I.; Boto, A.*; Miguélez, J. Metal-Free, One-Pot Conversion of Proline Derivatives into 2-Aryl-3-Iodo Pyrrolidines by a Sequential Scission–iodination–arylation Process. Org. Biomol. Chem. 2014, 12 (47), 9547–9556. DOI: 10.1039/C4OB01372G
7. Romero Estudillo, I. O.; Boto, A. Procedimiento de Modificación de Derivados de Aminoácidos Y Péptidos, Compuestos 5 Obtenidos Y Utilización. 2014. DOI: 10261/123862
6. Romero‐Estudillo, I.; Batchu, V. R.; Boto, A.* One‐Pot Conversion of Amino Acids into 2, 5‐Disubstituted Oxazoles: No Metals Needed. Adv. Synth. Catal. 2014, 356 (18), 3742–3748. DOI: 10.1002/adsc.201400496
5. Romero Estudillo, I. O.; Boto, A. Method for Modifying Derivatives of Amino Acids and Peptides, Compounds Produced, and Use. 2014. DOI: 10261/125023
2013
4. Romero-Estudillo, I.; Boto, A.* Creating Diversity by Site-Selective Peptide Modification: A Customizable Unit Affords Amino Acids with High Optical Purity. Org. Lett. 2013, 15 (22), 5778–5781. DOI: 10.1021/ol402800a
2012
3. Boto, A.*; Romero Estudillo, I. O. Procedimiento de Obtención de Amino Alcoholes Y Diaminas Quirales. 2012. DOI: 10261/75641
2. Boto, A.*; Romero Estudillo, I. O. Method for Obtaining Amino Alcohols and Chiral Diamines. 2012. DOI: 10261/76048
2011
1. Boto, A.*; Romero-Estudillo, I. One-Pot Stereoselective Synthesis of 1, 2-Amino Alcohol Derivatives. Org. Lett. 2011, 13 (13), 3426–3429. DOI: 10.1021/ol201173a
- Modificación selectiva de péptidos a través de procesos sostenibles
- Preparación de oxazolinas fosforiladas
- Procesos secuenciales para la modificación de aminoácidos
- Preparación de nuevos agentes antidiabéticos a través de procesos sostenibles
- Preparación de péptidos fluorescentes
- Modificación de aminoácidos
- Salazar Martínez Raúl Omar
- Hugo Casas Morales
- Itzel Antonia Bernal Evangelista
- Elizabeth Anahí Rebolledo Salgado
- Vázquez Arredondo Gil Arturo
Copyright © Todos los derechos reservados.