Silvia Marquina Bahena
Maestra en Química Orgánica, Universidad Autónoma del Estado de Morelos (1998)
Profesor-Investigador Asociado C
SNI: Nivel II
Líneas de Investigación:
Laboratorio de Fitoquímica
Cuerpo Académico: Productos Naturales
smarquina@uaem.mx| Teléfono: +52 777 329 79 97 Ext.6010
2023
37. Sánchez-Ramos, M., Guerrero-Alonso, A., Romero-Estrada, A., González-Christen, J., Alvarez, L., Acevedo-Fernández, J. J., Román-Guerrero, A., Cruz-Sosa, F., & Marquina-Bahena, S. (2024). Constituents from Ageratina pichinchensis and Their Inhibitory Effect on Nitric Oxide Production. Applied Sciences, 14(9), 3942. https://doi.org/10.3390/app14093942
36. García Méndez, M. del C., Encarnación-Guevara, S., Martínez Batallar, Á. G., Gómez-Caudillo, L., Bru-Martínez, R., Martínez Márquez, A., Selles Marchart, S., Tovar-Sánchez, E.,* Álvarez-Berber, L., Marquina Bahena, S., Perea-Arango, I., & Arellano-García, J. de J*. (2023). High variability of perezone content in rhizomes of Acourtia cordata wild plants, environmental factors related, and proteomic analysis. PeerJ, 11, e16136. DOI: 10.7717/peerj.16136
35. Sánchez-Ramos, M., Encarnación-García, J. G., Marquina-Bahena, S., Sánchez-Carranza, J. N., Bernabé-Antonio, A., Domínguez-Villegas, V., Cabañas-García, E., & Cruz-Sosa, F*. (2023). Cytotoxic Activity of Wild Plant and Callus Extracts of Ageratina pichinchensis and 2,3-Dihydrobenzofuran Isolated from a Callus Culture. Pharmaceuticals, 16(10), 1400. DOI: 10.3390/ph16101400
34. Sotelo-Leyva, C., Flores-Juárez, C., Bernal-Linares, A. K., González-Cortazar, M., Toledo-Hernández, E., Marquina-Bahena, S., Álvarez-Fitz, P., & Zamilpa, A*. (2023). Chemical composition of Bessera elegans (Asparagaceae) flower extracts and their insecticidal effect against Melanaphis sacchari Zehntner (Hemiptera: Aphididae). South African Journal of Botany, 156, 186–191. DOI: 10.1016/j.sajb.2023.03.015
33. Gress-Antonio, C. D*., Rivero-Perez, N., Marquina-Bahena, S., Alvarez, L., Zaragoza-Bastida, A., Martínez-Juárez, V. M., Sosa-Gutierrez, C. G., Ocampo-López, J., Zepeda-Bastida, A., & Ojeda-Ramírez, D.* (2023). Litsea glaucescens Kuth possesses bactericidal activity against Listeria monocytogenes. PeerJ, 11, e16522. DOI: 10.7717/peerj.16522
32. Ocampo-Bautista, F., Mussali-Galante, P.* Alvarez, L., Marquina-Bahena, S., Valencia-Cuevas, L., Valencia-A, S., & Tovar-Sánchez, E*. (2023). Natural Hybridization between Bursera bicolor × B. glabrifolia (Burseraceae) Complex: Molecular and Chemical Evidence. Forests, 14(7), 1382. DOI:10.3390/f14071382
31. Sánchez-Ramos, M*., Marquina-Bahena, S., Alvarez, L., Bernabé-Antonio, A., Cabañas-García, E., Román-Guerrero, A., & Cruz-Sosa, F. (2023). Obtaining 2,3-Dihydrobenzofuran and 3-Epilupeol from Ageratina pichinchensis (Kunth) R.King & Ho.Rob. Cell Cultures Grown in Shake Flasks under Photoperiod and Darkness, and Its Scale-Up to an Airlift Bioreactor for Enhanced Production. Molecules, 28(2), 578. DOI:10.3390/molecules28020578
2022
30. Sánchez-Ramos, M.; Berman-Bahena, S.; Alvarez, L.; Sánchez-Carranza, J. N.; Bernabé-Antonio, A.; Román-Guerrero, A.; Marquina-Bahena, S*.; Cruz-Sosa, F*. Effect of Plant Growth Regulators on Different Explants of Artemisia Ludoviciana under Photoperiod and Darkness Conditions and Their Influence on Achillin Production. Processes 2022, 10 (8), 1439. DOI: 10.3390/pr10081439.
29. Romero-Estrada, A.; Boto, A.; González-Christen, J.; Romero-Estudillo, I.; Garduño-Ramírez, M. L.; Razo-Hernández, R. S.; Marquina, S.; Maldonado-Magaña, A.; Columba-Palomares, M. C.; Sánchez-Carranza, J. N.; Alvarez, L.* Synthesis, Biological Evaluation, and Molecular Docking Study of 3-Amino and 3-Hydroxy- Seco A Derivatives of α-Amyrin and 3-Epilupeol as Inhibitors of COX-2 Activity and NF-kB Activation. J. Nat. Prod. 2022, acs.jnatprod.1c00827. DOI: 10.1021/acs.jnatprod.1c00827
2021
28. Sánchez-Ramos, M.; Marquina-Bahena, S.; Alvarez, L.; Román-Guerrero, A.; Bernabé-Antonio, A.; Cruz-Sosa, F*.
Phytochemical, Pharmacological, and Biotechnological Study of Ageratina Pichinchensis: A Native Species of Mexico. Plants
2021, 10 (10), 2225. DOI:10.3390/plants10102225
2020
27. Sánchez-Ramos, M.; Alvarez, L.; Romero-Estrada, A.; Bernabé-Antonio, A.; Marquina-Bahena, S.; Cruz-Sosa, F.* Establishment of a Cell Suspension Culture of Ageratina Pichinchensis (Kunth) for the Improved Production of Anti-Inflammatory Compounds. Plants 2020, 9 (10), 1398 DOI: 10.3390/plants9101398
26. Sánchez-Ramos, M.; Alvarez, L.; Romero-Estrada, A.; Bernabé-Antonio, A.; Marquina-Bahena, S.*; Cruz-Sosa, F.* Establishment of a Cell Suspension Culture of Ageratina Pichinchensis for the Improved Production of Anti-inflammatory Compounds. Preprints 2020, 2020080443. DOI: 10.20944/preprints202008.0443.v1
2019
25. Sanchez-Carranza; González-Maya; Razo-Hernández; Salas-Vidal; Nolasco-Quintana; Clemente-Soto; García-Arizmendi; Sánchez-Ramos; Marquina, S.*; Alvarez, L.* Achillin Increases Chemosensitivity to Paclitaxel, Overcoming Resistance and Enhancing Apoptosis in Human Hepatocellular Carcinoma Cell Line Resistant to Paclitaxel (Hep3B/PTX). Pharmaceutics 2019, 11 (10), 512 DOI: 10.3390/pharmaceutics11100512
ARTÍCULOS EN REVISTAS INDEXADAS
2021
28. Sánchez-Ramos, M.; Marquina-Bahena, S.; Alvarez, L.; Román-Guerrero, A.; Bernabé-Antonio, A.; Cruz-Sosa, F*.
Phytochemical, Pharmacological, and Biotechnological Study of Ageratina Pichinchensis: A Native Species of Mexico. Plants
2021, 10 (10), 2225. DOI:10.3390/plants10102225
2020
27. Sánchez-Ramos, M.; Alvarez, L.; Romero-Estrada, A.; Bernabé-Antonio, A.; Marquina-Bahena, S.; Cruz-Sosa, F.* Establishment of a Cell Suspension Culture of Ageratina Pichinchensis (Kunth) for the Improved Production of Anti-Inflammatory Compounds. Plants 2020, 9 (10), 1398 DOI: 10.3390/plants9101398
26. Sánchez-Ramos, M.; Alvarez, L.; Romero-Estrada, A.; Bernabé-Antonio, A.; Marquina-Bahena, S.*; Cruz-Sosa, F.* Establishment of a Cell Suspension Culture of Ageratina Pichinchensis for the Improved Production of Anti-inflammatory Compounds. Preprints 2020, 2020080443. DOI: 10.20944/preprints202008.0443.v1
2019
25. Sanchez-Carranza; González-Maya; Razo-Hernández; Salas-Vidal; Nolasco-Quintana; Clemente-Soto; García-Arizmendi; Sánchez-Ramos; Marquina, S.*; Alvarez, L.* Achillin Increases Chemosensitivity to Paclitaxel, Overcoming Resistance and Enhancing Apoptosis in Human Hepatocellular Carcinoma Cell Line Resistant to Paclitaxel (Hep3B/PTX). Pharmaceutics 2019, 11 (10), 512 DOI: 10.3390/pharmaceutics11100512
2018
24. Antúnez-Mojica, M.; Rojas-Sepúlveda, A.; Mendieta-Serrano, M.; Gonzalez-Maya, L.; Marquina, S.; Salas-Vidal, E.*; Alvarez, L.* Lignans from Bursera Fagaroides Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos. Molecules 2018, 24 (1), 8 DOI: 10.3390/molecules24010008
23. Marquina, S.; Maldonado-Santiago, M.; Sánchez-Carranza, J. N.; Antúnez-Mojica, M.; González-Maya, L.; Razo-Hernández, R. S.; Álvarez, L.* Design, Synthesis and QSAR Study of 2′-Hydroxy-4′-Alkoxy Chalcone Derivatives That Exert Cytotoxic Activity by the Mitochondrial Apoptotic Pathway. Bioorg. Med. Chem. 2018. DOI: 10.1016/j.bmc.2018.10.045
22. Sánchez-Ramos, M.; Bahena, S.; Romero-Estrada, A.; Bernabé-Antonio, A.; Cruz-Sosa, F.; Gonzálesssz-Christen, J.; Acevedo-Fernández, J.; Perea-Arango, I.; Alvarez, L.* Establishment and Phytochemical Analysis of a Callus Culture from Ageratina Pichinchensis (Asteraceae) and Its Anti-Inflammatory Activity. Molecules 2018, 23 (6), 1258. DOI: 10.3390/molecules23061258
2017
21. Sánchez-Carranza, J.; Alvarez, L.; Marquina-Bahena, S.; Salas-Vidal, E.; Cuevas, V.; Jiménez, E.; Veloz G., R.; Carraz, M.*; González-Maya, L.* Phenolic Compounds Isolated from Caesalpinia Coriaria Induce S and G2/M Phase Cell Cycle Arrest Differentially and Trigger Cell Death by Interfering with Microtubule Dynamics in Cancer Cell Lines. Molecules 2017, 22 (4), 666. DOI: 10.3390/molecules22040666
20. Moreno-Anzúrez, N.; Marquina, S.*; Alvarez, L.; Zamilpa, A.; Castillo-España, P.; Perea-Arango, I.; Torres, P.; Herrera-Ruiz, M.; Díaz García, E.; García, J.; Arellano-García, J.* A Cytotoxic and Anti-Inflammatory Campesterol Derivative from Genetically Transformed Hairy Roots of Lopezia Racemosa Cav. (Onagraceae). Molecules 2017, 22 (1), 118. DOI: 10.3390/molecules22010118
19. Mojica, M. A.; León, A.; Rojas-Sepúlveda, A. M.; Marquina, S.; Mendieta-Serrano, M. A.; Salas-Vidal, E.*; Villarreal, M. L.; Alvarez, L*. Aryldihydronaphthalene-Type Lignans from Bursera Fagaroides Var. Fagaroides and Their Antimitotic Mechanism of Action. RSC Adv. 2016, 6 (6), 4950–4959. DOI: 10.1039/C5RA23516B
2014
18. Pérez-Hernández, J.; González-Cortazar, M.*; Marquina, S.; Herrera-Ruiz, M.; Meckes-Fischer, M.; Tortoriello, J.; Cruz-Sosa, F.; del Pilar Nicasio-Torres, M. Sphaeralcic Acid and Tomentin, Anti-Inflammatory Compounds Produced in Cell Suspension Cultures of Sphaeralcea Angustifolia. Planta Med. 2014, 80 (02/03), 209–214. DOI: 10.1055/s-0033-1360302
17. González-Cortazar, M.; Herrera-Ruiz, M.*; Zamilpa, A.; Jiménez-Ferrer, E.; Marquina, S.; Álvarez, L.; Tortoriello, J. Anti-Inflammatory Activity and Chemical Profile of Galphimia Glauca. Planta Med. 2014, 80 (1), 90–96. DOI: 10.1055/s-0033-1360150
16. Salinas, R.; Arellano-García, J.; Perea-Arango, I.; Álvarez, L.; Garduño-Ramírez, M. L.; Marquina, S.; Zamilpa, A.; Castillo-España, P*. Production of the Anti-Inflammatory Compound 6-O-Palmitoyl-3-O-β-D-Glucopyranosylcampesterol by Callus Cultures of Lopezia Racemosa Cav.(Onagraceae). Molecules 2014, 19 (6), 8679–8690. DOI: 10.3390/molecules19068679
2013
15. González-Cortazar, M.; Maldonado-Abarca, A. M.; Jiménez-Ferrer, E.; Marquina, S.; Ventura-Zapata, E.; Zamilpa, A.; Tortoriello, J.*; Herrera-Ruiz, M. Isosakuranetin-5-O-Rutinoside: A New Flavanone with Antidepressant Activity Isolated from Salvia Elegans Vahl. Molecules 2013, 18 (11), 13260–13270. DOI: 10.3390/molecules181113260
2012
14. Alvarez-Fitz, P.; Alvarez, L.; Marquina, S.; Luna-Herrera, J.; Navarro-García, V. M*. Enzymatic Reduction of 9-Methoxytariacuripyrone by Saccharomyces Cerevisiae and Its Antimycobacterial Activity. Molecules 2012, 17 (7), 8464–8470. DOI: 10.3390/molecules17078464
13. Rojas-Sepúlveda, A. M.; Mendieta-Serrano, M.; Mojica, M. Y. A.; Salas-Vidal, E.; Marquina, S.; Villarreal, M. L.; Puebla, A. M.; Delgado, J. I.; Alvarez, L*. Cytotoxic Podophyllotoxin Type-Lignans from the Steam Bark of Bursera Fagaroides Var. Fagaroides. Molecules 2012, 17 (8), 9506–9519. DOI: 10.3390/molecules17089506
2011
12. Nava, E.; Dávila, Y.; Arellano, J.; Ortiz, A.; Alvárez, L.; Marquina, S.; Villarreal, M. L.* Genetic Transformation of Solanum Chrysotrichum by Agrobacterium Tumefaciens and the Production of Antifungal Saponins. Vitr. Cell. Dev. Biol. 2011, 47 (6), 650–657. DOI: 10.1007/s11627-011-9373-4
2009
11. Álvarez, L.*; Herrera-Arellano, A.; Marquina, S.; Tortoriello, J.; Zamilpa, A.; Gonzalez, M.; Villarreal, M. L.; Martínez-Rivera, M.; Lopez-Villegas, E. O.; Rodriguez-Tovar, A. V. Anti-Mycotic and Anti-Inflammatory Constituents from Four Mexican Medicinal Solanum Species. Curr. Top. steroid Res. Vol. 6 2009, 89–104.
10. López-Villegas, E. O.; Herrera-Arellano, A.*; de los Ángeles Martínez-Rivera, M.; Álvarez, L.; Cano-Nepauseno, M.; Marquina, S.; Rodríguez-Tovar, A. V.; Tortoriello, J. Ultrastructural Changes on Clinical Isolates of Trichophyton Rubrum, Trichophyton Mentagrophytes, and Microsporum Gypseum Caused by Solanum Chrysotrichum Saponin SC-2. Planta Med. 2009, 75 (14), 1517–1520. DOI: 10.1055/s-0029-1185810
9. Marquina, S.; Parra, J. L.; González, M.; Zamilpa, A.; Escalante, J.; Trejo-Hernández, M. R.; Álvarez, L.* Hydroxylation of the Diterpenes Ent-Kaur-16-En-19-Oic and Ent-Beyer-15-En-19-Oic Acids by the Fungus Aspergillus Niger. Phytochemistry 2009, 70 (17), 2017–2022. DOI: 10.1016/j.phytochem.2009.09.005
2008
8. Marquina, S.*; Garcia, Y.; Alvarez, L.; Tortoriello, J. 3-Acetoxy-7-Methoxyflavone, a Novel Flavonoid from the Anxiolytic Extract of Salvia Elegans (Lamiaceae). Nat. Prod. Commun. 2008, 3 (2), 185–188.
2005
7. Marquina, S.; Bonilla-Barbosa, J.; Alvarez, L.* Comparative Phytochemical Analysis of Four Mexican Nymphaea Species. Phytochemistry 2005, 66 (8), 921–927. DOI: 10.1016/j.phytochem.2005.02.027
2004
6. González, M.; Zamilpa, A.; Marquina, S.; Navarro, V.; Alvarez, L*. Antimycotic Spirostanol Saponins from Solanum Hispidum Leaves and Their Structure-Activity Relationships. J. Nat. Prod. 2004, 67 (6), 938–941. DOI: 10.1021/np0305019
2003
5. Álvarez, L.*; Zamilpa, A.; Marquina, S.; González, M. Two New Oleanolic Acid Saponins from the Roots of Viguiera Hypargyrea. Rev. la Soc. Química México 2003, 47 (2), 173–177. Online
2001
4. Meckes, M.; Gardufio-Ramirez, M. L.; Marquina, S.; Álvarez, A*. Iridoides Adicionales de La Planta Medicinal Astianthus Viminalis Y Su Actividad Hipoglucemiante Y Antihiperglucemiante. Rev. la Soc. Química Mex. 2001, 45, 195–199. Online
3. Ortega, A.; Garcı́a, P*. E.; Cárdenas, J.; Mancera, C.; Marquina, S.; del Carmen Garduño, M. L.; Maldonado, E. Methyl Dodonates, a New Type of Diterpenes with a Modified Clerodane Skeleton from Dodonaea Viscosa. Tetrahedron 2001, 57 (15), 2981–2989. DOI: 10.1016/S0040-4020(01)00161-2
2. Marquina, S.; Maldonado, N.; Garduño-Ramı́rez, M. L.; Aranda, E.; Villarreal, M. L.; Navarro, V.; Bye, R.; Delgado, G.; Álvarez, L*. Bioactive Oleanolic Acid Saponins and Other Constituents from the Roots of Viguiera Decurrens. Phytochemistry 2001, 56 (1), 93–97. DOI: 10.1016/S0031-9422(00)00283-1
1996
1. Álvarez, L.*; Marquina, S.; Villarreal, M. L.; Alonso, D.; Aranda, E.; Delgado, G. Bioactive Polyacetylenes from Bidens Pilosa. Planta Med. 1996, 62 (4), 355–357. DOI: 10.1055/s-2006-957902