PUBLICACIONES EN LIBROS (CAPÍTULOS)

1. Villarreal, M. L.; Nicasio, P.; Rojas, G.; Alvarez, L.; Quintero, R. Recent Progress in Biotechnology of Mexican Medicinal Plants. In Chemicals via Higher Plant Bioengineering; Springer, 1999; pp 221–233. DOI:10.1007/978-1-4615-4729-7_17

ARTÍCULOS EN REVISTAS INDEXADAS

2021

92. Sánchez-Ramos, M.; Marquina-Bahena, S.; Alvarez, L.; Román-Guerrero, A.; Bernabé-Antonio, A.; Cruz-Sosa, F*.

Phytochemical, Pharmacological, and Biotechnological Study of Ageratina Pichinchensis: A Native Species of Mexico. Plants

2021, 10 (10), 2225. DOI:10.3390/plants10102225

91. Antúnez-Mojica, M.; Romero-Estrada, A.; Hurtado-Díaz, I.; Miranda-Molina, A.; Alvarez, L.* Lignans from Bursera Fagaroides: Chemistry, Pharmacological Effects and Molecular Mechanism. A Current Review. Life 2021, 11 (7), 685 DOI: 10.3390/life11070685

90. Bernabé-Antonio, A.*; Sánchez-Sánchez, A.; Romero-Estrada, A.; Meza-Contreras, J. C.; Silva-Guzmán, J. A.; Fuentes-Talavera, F. J.; Hurtado-Díaz, I.; Alvarez, L.; Cruz-Sosa, F.* Establishment of a Cell Suspension Culture of Eysenhardtia Platycarpa: Phytochemical Screening of Extracts and Evaluation of Antifungal Activity. Plants 2021, 10 (2), 414 DOI: 10.3390/plants10020414

2020

89. Sánchez-Ramos, M.; Alvarez, L.; Romero-Estrada, A.; Bernabé-Antonio, A.; Marquina-Bahena, S.; Cruz-Sosa, F.* Establishment of a Cell Suspension Culture of Ageratina Pichinchensis (Kunth) for the Improved Production of Anti-Inflammatory Compounds. Plants 2020, 9 (10), 1398 DOI: 10.3390/plants9101398

88. Sánchez-Ramos, M.; Alvarez, L.; Romero-Estrada, A.; Bernabé-Antonio, A.; Marquina-Bahena, S.*; Cruz-Sosa, F.* Establishment of a Cell Suspension Culture of Ageratina Pichinchensis for the Improved Production of Anti-inflammatory Compounds. Preprints 2020, 2020080443. DOI: 10.20944/preprints202008.0443.v1

87. Maldonado-Santiago, M.; Santiago, Á.; Pastor, N.; Alvarez, L.*; Razo-Hernández, R. S.* Isatin Derivatives as DNA Minor Groove-Binding Agents: A Structural and Theoretical Study. Struct. Chem. 2020 DOI: 10.1007/s11224-020-01497-w

86. Méndez-López, L. F.; Garza-González, E.; Ríos, M. Y.; Ramírez-Cisneros, M. Á.; Alvarez, L.; González-Maya, L.; Sánchez-Carranza, J. N.; Camacho-Corona, M. del R.* Metabolic Profile and Evaluation of Biological Activities of Extracts from the Stems of Cissus Trifoliata. Int. J. Mol. Sci. 2020, 21 (3), 930 DOI: 10.3390/ijms21030930

2019

85. Leyva-Peralta, M. A.*; Robles-Zepeda, R. E.; Razo-Hernández, R. S.; Álvarez, L.; Lara, K. O.; Ruiz-Bustos, E.; Gálvez-Ruíz, J. C. Berberine as Source of Antiproliferative Hybrid Compounds: In Vitro Antiproliferative Activity and Quantitative Structure-Activity Relationship. Anticancer. Agents Med. Chem. 2019, 19 (15), 1820–1834 DOI: 10.2174/1871520619666190503121820

84. Sanchez-Carranza; González-Maya; Razo-Hernández; Salas-Vidal; Nolasco-Quintana; Clemente-Soto; García-Arizmendi; Sánchez-Ramos; Marquina, S.*; Alvarez, L.* Achillin Increases Chemosensitivity to Paclitaxel, Overcoming Resistance and Enhancing Apoptosis in Human Hepatocellular Carcinoma Cell Line Resistant to Paclitaxel (Hep3B/PTX). Pharmaceutics 2019, 11 (10), 512 DOI: 10.3390/pharmaceutics11100512

83. Stefani, T.; Garza-González, E.; Rivas-Galindo, V. M.; Rios, M. Y.; Alvarez, L.; Camacho-Corona, M. del R.* Hechtia Glomerata Zucc: Phytochemistry and Activity of Its Extracts and Major Constituents Against Resistant Bacteria. Molecules 2019, 24 (19), 3434 DOI: 10.3390/molecules24193434

82. Hurtado-Díaz; Sánchez-Carranza; Romero-Estrada; González-Maya; González-Christen; Herrera-Ruiz; Alvarez L.* 16-Hydroxy-Lycopersene, a Polyisoprenoid Alcohol Isolated from Tournefortia Hirsutissima, Inhibits Nitric Oxide Production in RAW 264.7 Cells and Induces Apoptosis in Hep3B Cells. Molecules 2019, 24 (13), 2366 DOI: 10.3390/molecules24132366

81. Porras-Domínguez, J. R.; Rodríguez-Alegría, M. E.; Miranda, A.; Alvarez Berber, L. P.; Edmundo, C.; López Munguía, A.* Frucooligosaccharides Purification: Complexing Simple Sugars with Phenylboronic Acid. Food Chem. 2019, 285, 204–212 DOI: 10.1016/j.foodchem.2019.01.130

80. Mendieta-Serrano, M. A.; Mendez-Cruz, F. J.; Antúnez-Mojica, M.; Schnabel, D.; Alvarez, L.; Cárdenas, L.; Lomelí, H.; Ruiz-Santiesteban, J. A.; Salas-Vidal, E.* NADPH-Oxidase-Derived Reactive Oxygen Species Are Required for Cytoskeletal Organization, Proper Localization of E-Cadherin and Cell Motility during Zebrafish Epiboly. Free Radic. Biol. Med. 2019, 130, 82–98. DOI: 10.1016/j.freeradbiomed.2018.10.416

2018

79. Antúnez-Mojica, M.; Rojas-Sepúlveda, A.; Mendieta-Serrano, M.; Gonzalez-Maya, L.; Marquina, S.; Salas-Vidal, E.*; Alvarez, L.* Lignans from Bursera Fagaroides Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos. Molecules 2018, 24 (1), 8 DOI: 10.3390/molecules24010008

78. Marquina, S.; Maldonado-Santiago, M.; Sánchez-Carranza, J. N.; Antúnez-Mojica, M.; González-Maya, L.; Razo-Hernández, R. S.; Álvarez, L.* Design, Synthesis and QSAR Study of 2′-Hydroxy-4′-Alkoxy Chalcone Derivatives That Exert Cytotoxic Activity by the Mitochondrial Apoptotic Pathway. Bioorg. Med. Chem. 2018. DOI: 10.1016/j.bmc.2018.10.045

77. Raga-Carbajal, E.; López-Munguía, A.; Alvarez, L.; Olvera, C.* Understanding the Transfer Reaction Network behind the Non-Processive Synthesis of Low Molecular Weight Levan Catalyzed by Bacillus Subtilis Levansucrase. Sci. Rep. 2018, 8 (1), 15035. DOI: 10.1038/s41598-018-32872-7

76. Sánchez-Ramos, M.; Bahena, S.; Romero-Estrada, A.; Bernabé-Antonio, A.; Cruz-Sosa, F.; Gonzálesssz-Christen, J.; Acevedo-Fernández, J.; Perea-Arango, I.; Alvarez, L.* Establishment and Phytochemical Analysis of a Callus Culture from Ageratina Pichinchensis (Asteraceae) and Its Anti-Inflammatory Activity. Molecules 2018, 23 (6), 1258. DOI: 10.3390/molecules23061258

75. Sánchez-Carranza, J.; Díaz, J.; Redondo-Horcajo, M.; Barasoain, I.; Alvarez, L.; Lastres, P.; Romero-Estrada, A.; Aller, P.*; González-Maya, L.* Gallic Acid Sensitizes Paclitaxel-Resistant Human Ovarian Carcinoma Cells through an Increase in Reactive Oxygen Species and Subsequent Downregulation of ERK Activation. Oncol. Rep. 2018. DOI: 10.3892/or.2018.6382

74. López-Lara, I. M.; Nogales, J.; Pech-Canul, Á.; Calatrava-Morales, N.; Bernabéu-Roda, L. M.; Durán, P.; Cuéllar, V.; Olivares, J.; Alvarez, L.; Palenzuela-Bretones, D.; Romero, M.; Heeb, S.; Cámara, M.; Geiger, O.; Soto, M. J.* 2-Tridecanone Impacts Surface-Associated Bacterial Behaviours and Hinders Plant-Bacteria Interactions. Environ. Microbiol. 2018. DOI:10.1111/1462-2920.14083

73 .Rosas-Galván, N. S.; Martínez-Morales, F.; Marquina-Bahena, S.; Tinoco-Valencia, R.; Serrano-Carreón, L.; Bertrand, B.; León-Rodríguez, R.; Guzmán-Aparicio, J.; Alvaréz-Berber, L.; Trejo-Hernández, M. R.* Improved Production, Purification, and Characterization of Biosurfactants Produced by Serratia Marcescens SM3 and Its Isogenic SMRG-5 Strain. Biotechnol. Appl. Biochem. 2018, 65 (5), 690–700 DOI: 10.1002/bab.1652

2017

72. Herrera, Y.; Contreras, S.; Hernández, M.; Álvarez, L.; Mora, Y.; Encarnación-Guevara, S.* Displacers Improve the Selectivity of Phosphopeptide Enrichment by Metal Oxide Affinity Chromatography. Bol. Med. Hosp. Infant. Mex. 2017, 74 (3), 200–207. DOI: 10.1016/j.bmhimx.2017.03.008

71. Mendieta-Serrano, M.*; Méndez-Cruz, F. J.; Cárdenas, L.; Antúnez-Mojica, M.; Alvarez, L.; Schnabel-Peraza, D.; Lomelí, H.; Salas-Vidal, E. Reactive Oxygen Species Dynamics in Developing Zebrafish Embryos. Mech. Dev. 2017, 145, S66. DOI: 10.1016/j.mod.2017.04.147

70. Gutiérrez-Gutiérrez, F.; Puebla-Pérez, A.; González-Pozos, S.; Hernández-Hernández, J.; Pérez-Rangel, A.; Alvarez, L.; Tapia-Pastrana, G.; Castillo-Romero, A.* Antigiardial Activity of Podophyllotoxin-Type Lignans from Bursera Fagaroides Var. Fagaroides. Molecules 2017, 22 (5), 799. DOI: 10.3390/molecules22050799

69. Sánchez-Carranza, J.; Alvarez, L.; Marquina-Bahena, S.; Salas-Vidal, E.; Cuevas, V.; Jiménez, E.; Veloz G., R.; Carraz, M.*; González-Maya, L.* Phenolic Compounds Isolated from Caesalpinia Coriaria Induce S and G2/M Phase Cell Cycle Arrest Differentially and Trigger Cell Death by Interfering with Microtubule Dynamics in Cancer Cell Lines. Molecules 2017, 22 (4), 666. DOI: 10.3390/molecules22040666

68. Moreno-Anzúrez, N.; Marquina, S.*; Alvarez, L.; Zamilpa, A.; Castillo-España, P.; Perea-Arango, I.; Torres, P.; Herrera-Ruiz, M.; Díaz García, E.; García, J.; Arellano-García, J.* A Cytotoxic and Anti-Inflammatory Campesterol Derivative from Genetically Transformed Hairy Roots of Lopezia Racemosa Cav. (Onagraceae). Molecules 2017, 22 (1), 118. DOI: 10.3390/molecules22010118

2016

67. Mojica, M. A.; León, A.; Rojas-Sepúlveda, A. M.; Marquina, S.; Mendieta-Serrano, M. A.; Salas-Vidal, E.*; Villarreal, M. L.; Alvarez, L.* Aryldihydronaphthalene-Type Lignans from Bursera Fagaroides Var. Fagaroides and Their Antimitotic Mechanism of Action. RSC Adv. 2016, 6 (6), 4950–4959. DOI: 10.1039/C5RA23516B

66. Antúnez-Mojica, M.; Rodríguez-Salarichs, J.; Redondo-Horcajo, M.; León, A.; Barasoain, I.; Canales, Á.; Cañada, F. J.; Jiménez-Barbero, J.; Alvarez, L.*; Díaz, J. F.* Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin. J. Nat. Prod. 2016, 79 (8), 2113–2121. DOI: 10.1021/acs.jnatprod.6b00428

65. Romero-Estrada, A.; Maldonado-Magaña, A.; González-Christen, J.; Bahena, S. M.; Garduño-Ramírez, M. L.; Rodríguez-López, V.; Alvarez, L.* Anti-Inflammatory and Antioxidative Effects of Six Pentacyclic Triterpenes Isolated from the Mexican Copal Resin of Bursera Copallifera. BMC Complement. Altern. Med. 2016, 16 (1), 422. DOI: 10.1186/s12906-016-1397-1

64. Quezada-Lázaro, R.; Fernández-Zuñiga, E. A.; García, A.; Garza-González, E.; Alvarez, L.; del Rayo Camacho-Corona, M. ANTIMYCOBACTERIAL COMPOUNDS FROM NASTURTIUM OFFICINALE. African J. Tradit. Complement. Altern. Med. 2016, 13 (2). Online.

2015

63. Bernabé-Antonio, A.; Álvarez, L.; Buendía-González, L.; Maldonado-Magaña, A.; Cruz-Sosa, F.* Accumulation and Tolerance of Cr and Pb Using a Cell Suspension Culture System of Jatropha Curcas. Plant Cell, Tissue Organ Cult. 2015, 120 (1), 221–228. DOI: 10.1007/s11240-014-0597-y

62. Alejandre-García, I.; Álvarez, L.; Cardoso-Taketa, A.; González-Maya, L.; Antúnez, M.; Salas-Vidal, E.; Díaz, J. F.; Marquina-Bahena, S.; Villarreal, M. L.* Cytotoxic Activity and Chemical Composition of the Root Extract from the Mexican Species Linum Scabrellum: Mechanism of Action of the Active Compound 6-Methoxypodophyllotoxin. Evidence-Based Complement. Altern. Med. 

2015, 2015. DOI: 10.1155/2015/298463

61. Bernabé-Antonio, A.*; Álvarez, L.; Salcedo-Pérez, E.; Toral, F. A. L.-D.; Anzaldo-Hernández, J.; Cruz-Sosa, F. Fatty Acid Profile of Intact Plants of Two Different Sites and Callus Cultures Derived from Seed and Leaf Explants of Calophyllum Brasiliense Cambess: A New Resource of Non-Edible Oil. Ind. Crops Prod. 2015, 77, 1014–1019. DOI: 10.1016/j.indcrop.2015.10.004

2014

60. Salinas, R.; Arellano-García, J.; Perea-Arango, I.; Álvarez, L.; Garduño-Ramírez, M. L.; Marquina, S.; Zamilpa, A.; Castillo-España, P.* Production of the Anti-Inflammatory Compound 6-O-Palmitoyl-3-O-β-D-Glucopyranosylcampesterol by Callus Cultures of Lopezia Racemosa Cav.(Onagraceae). Molecules 2014, 19 (6), 8679–8690. DOI: 10.3390/molecules19068679

59. Esquivel-Ferriño, P. C.; Clemente-Soto, A. F.; Ramírez-Cabriales, M. Y.; Garza-González, E.; Álvarez, L.; Camacho-Corona, M. del R*. Volatile Constituents Identified in Hexane Extract of Citrus Sinensis Peel and Anti-Mycobacterial Tuberculosis Activity of Some of Its Constituents. J. Mex. Chem. Soc. 2014, 58 (4), 431–434. Online.

58. González-Cortazar, M.; Herrera-Ruiz, M.*; Zamilpa, A.; Jiménez-Ferrer, E.; Marquina, S.; Álvarez, L.; Tortoriello, J. Anti-Inflammatory Activity and Chemical Profile of Galphimia Glauca. Planta Med. 2014, 80 (1), 90–96. DOI: 10.1055/s-0033-1360150

2013

57. Moreno-Escobar, J. A.; Alvarez, L.*; Rodríguez-López, V.; Bahena, S. M.* Cytotoxic Glucosydic Iridoids from Veronica Americana. Phytochem. Lett. 2013, 6 (4), 610–613. DOI: 10.1016/j.phytol.2013.07.017

2012

56. Sandoval-Montemayor, N. E.; García, A.; Elizondo-Treviño, E.; Garza-González, E.; Alvarez, L.; del Rayo Camacho-Corona, M.* Chemical Composition of Hexane Extract of Citrus Aurantifolia and Anti-Mycobacterium Tuberculosis Activity of Some of Its Constituents. Molecules 2012, 17 (9), 11173–11184. DOI: 10.3390/molecules170911173

55. Rojas-Sepúlveda, A. M.; Mendieta-Serrano, M.; Mojica, M. Y. A.; Salas-Vidal, E.; Marquina, S.; Villarreal, M. L.; Puebla, A. M.; Delgado, J. I.; Alvarez, L.* Cytotoxic Podophyllotoxin Type-Lignans from the Steam Bark of Bursera Fagaroides Var. Fagaroides. Molecules 2012, 17 (8), 9506–9519. DOI: 10.3390/molecules17089506

54. Alvarez-Fitz, P.; Alvarez, L.; Marquina, S.; Luna-Herrera, J.; Navarro-García, V. M.* Enzymatic Reduction of 9-Methoxytariacuripyrone by Saccharomyces Cerevisiae and Its Antimycobacterial Activity. Molecules 2012, 17 (7), 8464–8470. DOI: 10.3390/molecules17078464

53. Miranda-Molina, A.; Marquina-Bahena, S.; López-Munguía, A.; Álvarez, L.*; Castillo, E.* Regioselective Glucosylation of Inositols Catalyzed by Thermoanaerobacter Sp. CGTase. Carbohydr. Res. 2012, 360, 93–101. DOI: 10.1016/j.carres.2012.08.002

2011

52. Pech-Canul, Á.; Nogales, J.; Miranda-Molina, A.; Álvarez, L.; Geiger, O.; Soto, M. J.; López-Lara, I. M. FadD Is Required for Utilization of Endogenous Fatty Acids Released from Membrane Lipids. J. Bacteriol. 2011, 193 (22), 6295–6304. DOI: 10.1128/JB.05450-11

51. Nava, E.; Dávila, Y.; Arellano, J.; Ortiz, A.; Alvárez, L.; Marquina, S.; Villarreal, M. L.* Genetic Transformation of Solanum Chrysotrichum by Agrobacterium Tumefaciens and the Production of Antifungal Saponins. Vitr. Cell. Dev. Biol. 2011, 47 (6), 650–657. DOI: 10.1007/s11627-011-9373-4

2010

50. Ojeda, D.; Jiménez-Ferrer, E.; Zamilpa, A.; Herrera-Arellano, A.; Tortoriello, J.; Alvarez, L.* Inhibition of Angiotensin Convertin Enzyme (ACE) Activity by the Anthocyanins Delphinidin-and Cyanidin-3-O-Sambubiosides from Hibiscus Sabdariffa. J. Ethnopharmacol. 2010, 127 (1), 7–10. DOI: 10.1016/j.jep.2009.09.059

49. Miranda-Molina, A.; López-Munguía, A.; San Román, M. L.; Escalante, J.; Leyva, M. A.; Puebla, A. M.; Castillo, E.*; Álvarez, L.* Stereoselective Enzymatic Synthesis of Monoglucosyl-Myo-Inositols with in Vivo Anti-Inflammatory Activity. Tetrahedron: Asymmetry 2010, 21 (1), 43–50. DOI: 10.1016/j.tetasy.2009.12.009

2009

48. Marquina, S.; Parra, J. L.; González, M.; Zamilpa, A.; Escalante, J.; Trejo-Hernández, M. R.; Álvarez, L.* Hydroxylation of the Diterpenes Ent-Kaur-16-En-19-Oic and Ent-Beyer-15-En-19-Oic Acids by the Fungus Aspergillus Niger. Phytochemistry 2009, 70 (17), 2017–2022. DOI: 10.1016/j.phytochem.2009.09.005

47. López-Villegas, E. O.; Herrera-Arellano, A.; de los Ángeles Martínez-Rivera, M.; Álvarez, L.; Cano-Nepauseno, M.; Marquina, S.; Rodríguez-Tovar, A. V.; Tortoriello, J. Ultrastructural Changes on Clinical Isolates of Trichophyton Rubrum, Trichophyton Mentagrophytes, and Microsporum Gypseum Caused by Solanum Chrysotrichum Saponin SC-2. Planta Med. 2009, 75 (14), 1517–1520. DOI: 10.1055/s-0029-1185810

46. Alvarez, L.; Herrera-Arellano, A.; Marquina, S.; Tortoriello, J.; Zamilpa, A.; Gonzalez, M.; Villarreal, M. L.; Martínez-Rivera, M.; Lopez-Villegas, E. O.; Rodriguez-Tovar, A. V. Anti-Mycotic and Anti-Inflammatory Constituents from Four Mexican Medicinal Solanum Species. Curr. Top. steroid Res. Vol. 6 2009, 89–104. Online.

2008

45. Herrera, Y.; Okoh, A. I.; Alvarez, L.; Robledo, N.; Trejo-Hernández, M. R.* Biodegradation of 2, 4- Dichlorophenol by a Bacillus Consortium. World J. Microbiol. Biotechnol. 2008, 24 (1), 55–60. DOI: 10.1007/s11274-007-9437-0

44. Marquina, S.; Garcia, Y.; Alvarez, L.; Tortoriello, J. 3-Acetoxy-7-Methoxyflavone, a Novel Flavonoid from the Anxiolytic Extract of Salvia Elegans (Lamiaceae). Nat. Prod. Commun. 2008, 3 (2), 185–188.

43. Nava, E.; Dávila, Y.; Arellano, J.; Álvarez, L.; Herrera, Y.; Ortiz, A.; Villarreal, M. L. High–yield Production of Antifungal Saponins Using Transformed Cell Suspension Cultures of the Mexican Species Solanum Chrysotrichum. Planta Med. 2008, 74 (9), PG72. DOI: 10.1055/s-0028-1084824

2007

42. Herrera-Arellano, A.; de los Angeles Martínez-Rivera, M.; Hernández-Cruz, M.; López-Villegas, E. O.; Rodríguez-Tovar, A. V.; Alvarez, L.; Marquina-Bahena, S.; Navarro-García, V. M.; Tortoriello, J. Mycological and Electron Microscopic Study of Solanum Chrysotrichum Saponin SC-2 Antifungal Activity on Candida Species of Medical Significance. Planta Med. 2007, 73 (15), 1568–1573. DOI: 10.1055/s-2007-993744

41. Alvarez, L.; Castillo-España, P.; Tortoriello, J.; Herrera-Arellano, A. Valeriana Edulis Subsp. Procera, an Endangered Mexican Medicinal Plant. Massive Regeneration and Its Pharmacological Relevance. Curr. Top. Phytochem. Vol. 8 2007, 85–96. PDF

2006

40. Argotte-Ramos, R.; Ramírez-Avila, G.; Rodríguez-Gutiérrez, M. del C.; Ovilla-Muñoz, M.; Lanz-Mendoza, H.; Rodríguez, M. H.; González-Cortazar, M.; Alvarez, L.* Antimalarial 4-Phenylcoumarins from the Stem Bark of Hintonia Latiflora. J. Nat. Prod. 2006, 69 (10), 1442–1444. DOI: 10.1021/np060233p

39. Narváez-Mastache, J. M.; Garduño-Ramírez, M. L.; Alvarez, L.; Delgado, G.* Antihyperglycemic Activity and Chemical Constituents of Eysenhardtia Platycarpa. J. Nat. Prod. 2006, 69 (12), 1687–1691. DOI: 10.1021/np060166z

38. Herrera-Ruiz, M.; González-Cortazar, M.; Jiménez-Ferrer, E.; Zamilpa, A.; Álvarez, L.; Ramírez, G.; Tortoriello, J.* Anxiolytic Effect of Natural Galphimines from Galphimia Glauca and Their Chemical Derivatives. J. Nat. Prod. 2006, 69 (1), 59–61. DOI: 10.1021/np050305x

2005

37. Marquina, S.; Bonilla-Barbosa, J.; Alvarez, L.* Comparative Phytochemical Analysis of Four Mexican Nymphaea Species. Phytochemistry 2005, 66 (8), 921–927. DOI: 10.1016/j.phytochem.2005.02.027

36. González-Cortazar, M.; Tortoriello, J.; Alvarez, L.* Norsecofriedelanes as Spasmolytics, Advances of Structure-Activity Relationships. Planta Med. 2005, 71 (8), 711–716. DOI: 10.1055/s-2005-871224

35. Herrera-Salgado, Y.; Garduño-Ramírez, M. L.; Vázquez, L.; Rios, M. Y.; Alvarez, L.* Myo-Inositol-Derived Glycolipids with Anti-Inflammatory Activity from Solanum L Anceolatum. J. Nat. Prod. 2005, 68 (7), 1031–1036. DOI: 10.1021/np050054s

34. Caspeta, L.; Nieto, I.; Zamilpa, A.; Alvarez, L.; Quintero, R.; Villarreal, M. L. Solanum Chrysotrichum Hairy Root Cultures: Characterization, Scale-up and Production of Five Antifungal Saponins for Human Use. Planta Med. 2005, 71 (11), 1084–1087. DOI: 10.1055/s-2005-873170

2004

33. González, M.; Zamilpa, A.; Marquina, S.; Navarro, V.; Alvarez, L*. Antimycotic Spirostanol Saponins from Solanum Hispidum Leaves and Their Structure-Activity Relationships. J. Nat. Prod. 2004, 67 (6), 938–941. DOI: 10.1021/np0305019

2003

32. Herrera-Arellano, A.; Rodríguez-Soberanes, A.; de los Angeles Martínez-Rivera, M.; Martínez-Cruz, E.; Zamilpa, A.; Alvarez, L.; Tortoriello, J. Effectiveness and Tolerability of a Standardized Phytodrug Derived from Solanum Chrysotrichum on Tinea Pedis: A Controlled and Randomized Clinical Trial. Planta Med. 2003, 69 (5), 390–395. DOI: 10.1055/s-2003-39710

31. Fraga, B. M.*; Alvarez, L.; Suárez, S. Biotransformation of the Diterpenes Epicandicandiol and Candicandiol by Mucor Plumbeus. J. Nat. Prod. 2003, 66 (3), 327–331. DOI: 10.1021/np020420x

30. Alvarez, L.*; Zamilpa, A.; Marquina, S.; González, M. Two New Oleanolic Acid Saponins from the Roots of Viguiera Hypargyrea. Rev. la Soc. Química México 2003, 47 (2), 173–177. Online.

2002

29. Zamilpa, A.*; Tortoriello, J.; Navarro, V.; Delgado, G.; Alvarez, L.* Five New Steroidal Saponins from Solanum c Hrysotrichum Leaves and Their Antimycotic Activity. J. Nat. Prod. 2002, 65 (12), 1815–1819. DOI: 10.1021/np020261h

28. Zamilpa, A.; Tortoriello, J.; Navarro, V.; Delgado, G.; Alvarez, L.* Antispasmodic and Antimicrobial Diterpenic Acids from Viguiera Hypargyrea Roots. Planta Med. 2002, 68 (3), 281–283. DOI: 10.1055/s-2002-23146

27. Castillo, P.; Zamilpa, A.; Márquez, J.; Hernández, G.; Lara, M.; Alvarez, L.* Comparative Study of Differentiation Levels and Valepotriate Content of in Vitro Cultures and Regenerated and Wild Plants of Valeriana E Dulis Ssp. P Rocera. J. Nat. Prod. 2002, 65 (4), 573–575. DOI: 10.1021/np0104267

26. Villarreal, M. L.; Alvárez, L.; Quintero, R. Solanum Chrysotrichum (Schldl): Distribution, Identification of the Antifungal SC-1 Saponin, in Vitro Propagation, Cell Suspension Cultures, Large-Scale Production of SC-1. In Medicinal and Aromatic Plants XII; Springer, 2002; pp 252–267. DOI: 10.1007/978-3-662-08616-2_14 

25. ML, V.; ALVAREZ, L.; QUINTERO, R. Propagation, Cell Suspension Cultures, Large-Scale. Med. Aromat. Plants XII 2002, 12, 252.

2001

24. Herrera-Arellano, A.; Luna-Villegas, G.; Cuevas-Uriostegui, M. L.; Alvarez, L.; Vargas-Pineda, G.; Zamilpa-Alvarez, A.; Tortoriello, J. Polysomnographic Evaluation of the Hypnotic Effect of Valeriana Edulis Standardized Extract in Patients Suffering from Insomnia. Planta Med. 2001, 67 (8), 695–699. DOI: 10.1055/s-2001-18344

23. Marquina, S.; Maldonado, N.; Garduño-Ramı́rez, M. L.; Aranda, E.; Villarreal, M. L.; Navarro, V.; Bye, R.; Delgado, G.; Alvarez, L.* Bioactive Oleanolic Acid Saponins and Other Constituents from the Roots of Viguiera Decurrens. Phytochemistry 2001, 56 (1), 93–97. DOI: 10.1016/S0031-9422(00)00283-1

22. Alvarez, L.; del Carmen Pérez, M.; González, J. L.; Navarro, V.; Villarreal, M. L.; Olson, J. O. SC-1, an Antimycotic Spirostan Saponin from Solanum Chrysotrichum. Planta Med. 2001, 67 (4), 372–374. DOI: 10.1055/s-2001-14332

1999

21. Alvarez, L.*; Delgado, G. C-and O-Glycosyl-α-Hydroxydihydrochalcones from Eysenhardtia Polystachya. Phytochemistry 1999, 50 (4), 681–687. DOI: 10.1016/S0031-9422(98)00576-7

1998

20. Alvarez, L.*; Rios, M. Y.; Esquivel, C.; Chávez, M. I.; Delgado, G.*; Aguilar, M. I.; Villarreal, M. L.; Navarro, V. Cytotoxic Isoflavans from Eysenhardtia P Olystachya. J. Nat. Prod. 1998, 61 (6), 767–770. DOI: 10.1021/np970586b

1996

19. Alvarez, L.*; Marquina, S.; Villarreal, M. L.; Alonso, D.; Aranda, E.; Delgado, G. Bioactive Polyacetylenes from Bidens Pilosa. Planta Med. 1996, 62 (4), 355–357. DOI: 10.1055/s-2006-957902

1994

18. Delgado, G.*; Hernández, J.; Chávez, M. I.; Alvarez, L.; Gonzaga, V.; Martínez, E. Di-and Triterpenoid Acids from Lepechinia Caulescens. Phytochemistry 1994, 37 (4), 1119–1121. DOI: 10.1016/S0031-9422(00)89540-0

17. Alvarez, L.*; Nunez, M.; del Carmen Pérez, M.; Villarreal, M. L.; Delgado, G. Chemical and Biological Study of Astianthus Viminalis. Planta Med. 1994, 60 (1), 98. DOI: 10.1055/s-2006-959424

16. Villarreal, M. L.*; Alvarez, L.; Alonso, D. Et, Al. 1994 Cytotoxic and Antimicrobial Screening of Selected Terpenoids from Asteraceae Species. J. Ethnopharmacol 42, 25–29. DOI: 10.1016/0378-8741(94)90019-1

1992

15. Delgado, G.; Rios, M. Y.; Colin, L.; Garcia, P. E.; Alvarez, L. Consituents of Borrichia Frutescens. Fitoterapia 1992, 63 (3), 273–274.

14. Alvarez, L.; Velasco, A.; Villarreal, M. L.; Delgado, G.; Chavez, M. I.; Del Río, F. Constituents of a Population of Ambrosia Hispida and Cytotoxic Evaluation of Its Major Constituent, Hispidulin. Fitoterapia 1992, 63, 366–367. 

13. Delgado, I.*; Sánchez, E.; Hernández, J.; Chávez, M. I.; Alvarez, L.; Martínez, E. Abietanoid Acid from Lepechinia Caulescens. Phytochemistry 1992, 31 (9), 3159–3161. DOI: 10.1016/0031-9422(92)83466-C

1988

12. Alvarez, L.; Delgado, G.* Acid-Catalyzed Transformations of the Heliangolide 15-Hydroxyacetylleptocarpin. J. Org. Chem. 1988, 53 (23), 5527–5530. DOI: 10.1021/jo00258a023

11. Delgado, G.*; Chavez, M. I.; Alvarez, L. New Seco-Pseudoguaianolides and Other Terpenoids from a Population of Ambrosia Confertiflora. J. Nat. Prod. 1988, 51 (1), 83–87. DOI: 10.1021/np50055a011

10. Alvarez, L.; Delgado, G.* Acid-catalyzed cyclization of 15-hydroxy-acetylleptocarpin. In Abstracts of Papers of the American Chemical Society; Amer Chemical Soc 1155 16th ST, NW, Washington, DC 20036, 1988; vol. 195, p 436–orgn. DOI: 10.1021/jo00258a023

1987

9. Delgado, G.*; Alvarez, L.; Huerta, E.; de Vivar, A. R.; Mata, R. Carbon‐13 NMR Spectra of Some Pseudoguaianolides. Magn. Reson. Chem. 1987, 25 (3), 201–202. DOI: 10.1002/mrc.1260250304

8. Delgado, G.*; Alvarez, L.; Soriano-García, M.; Toscano, R. A.; Mata, R.; Pereda-Miranda, R. Stereochemistry of the Ester Side Chain of the Germacranolides of Viguiera Hypargyrea. J. Nat. Prod. 1987, 50 (2), 273–276. DOI: 10.1021/np50050a034

1986

7. Mata, R.*; Navarrete, A.; Alvarez, L.; Pereda-Miranda, R.; Delgado, G.; de Vivarf, A. R. Flavonoids and Terpenoids of Chenopodium Graveolens. Phytochemistry 1986, 26 (1), 191–193. DOI: 10.1016/S0031-9422(00)81509-5

 6. Delgado, G.; Cardenas, X.; Alvarez, L.; DE VIVAR, A. R.; Pereda-Miranda, R. New Oleanane and Isopimarane Terpenoids from Lepechinia Glomerata. J. Chem. Res. Synopses 1986, No. 8, 286–287. 

5. Delgado, G.*; Alvarez, L.; Mata, R.; Pereda-Miranda, R.; de Vivar, A. R.; Villaseñor, J. L. Terpenoids from Viguiera Latibracteate and Viguiera Greggii. J. Nat. Prod. 1986, 49 (6), 1165–1166. DOI: 10.1021/np50048a054

1985

4. Alvarez, L.; Mata, R.; Delgado, G.; de Vivar, A. R. Sesquiterpene Lactones from Viguiera Hypargyrea. Phytochemistry 1985, 24 (12), 2973–2976. DOI: 10.1016/0031-9422(85)80038-8

3. Delgado, G.*; Alvarez, L.; de Vivar, A. R. 15-Hydroxy-Acetylerioflorin and Other Constituents from Viguiera Linearis. Phytochemistry 1985, 24 (11), 2736–2738. DOI: 10.1016/S0031-9422(00)80712-8

1984

2. Delgado, G.*; Alvarez, L.; de Vivar, A. R. Terpenoids and a Flavan-3-Ol from Viguiera Quinqueradiata. Phytochemistry 1984, 23 (3), 675–678. DOI: 10.1016/S0031-9422(00)80405-7

1. Delgado, G.*; Alvarez, L.; de Vivar, A. R. 15-Oxo-Zoapatlin, a Diterpene Lactone from Viguiera Maculata. Phytochemistry 1984, 23 (11), 2674–2675. DOI: 10.1016/S0031-9422(00)84125-4

• Síntesis de derivados de chalconas y su evaluación citotóxica. 
• Estudio químico de Lepidium virginicum y Lippia alba y su efecto antimicrobiano.
• Búsqueda de compuestos bioactivos de plantas medicinales mexicanas. 
• Semisíntesis de derivados del ácido ursólico con actividad antiinflamatoria. 
• Estudio metabolómico de especies del género Pinus. 
• Estudio del efecto citotóxico en células humanas del ácido gálico la achillina. 
• Establecimiento de un cultivo de células en suspensión para la producción de MS con actividad cicatrizante de Eupatorium asohembornianum. 
• Diseño in sílico, síntesis y evaluación citotóxica de derivados de chalconas.

1. Fidel Ocampo Bautista
2. Gabriela Ivonne Serrano Villanueva
3. Juan Pablo Díaz Abad
4. María Nancy Pérez Mejía
5. Yazmin Brisceida Jiménez Nevarez
6. Modesto Millan Ponce
7. Angelica Salinas Carrasco
8. Laura Solís Salinas
9. Israel Hurtado Díaz
10. Israel Domínguez Valle
11. Laura Solis Salinas
12.  Domínguez Valle Israel
13. Sheyla Hernández Carrera
14. Magdala Zulema Figueroa Suárez
15. Blanca Elizabeth Hernández Solano  
16. Jorge Leonit Morales Juárez
17. Ninfa Yaret Nolasco Quintana
18. Cuauhtémoc Virto Salgado
19. Danna Michelle Madrid Carpio 
20. Iker Alejandro Sánchez García
21. Valentina Torres Landa
22. Hector Uriel Garcia Estrada
23. María José Vega Yáñez
24. Marvin Jared Rodríguez Ramírez