PH- León Rivera Ismael
Ismael León Rivera

Doctorado en Química, (1998)
Profesor- Titular B
SNI: Nivel II
Líneas de Investigación: Productos Naturales
Cuerpo Académico: Química Farmacéutica y Biotecnología
ORCID 0000-0002-5202-1837| Google Académico 
2019

67. Rios, M. Y.; León-Rivera, I.; Ríos-Gomez, R.; Córdova-Albores, L. C.; Berenice Aguilar-Guadarrama, A.* Phytotoxic and Nematicide Evaluation of Croton Ehrenbergii (Euphorbiaceae). Pest Manag. Sci. 2019. DOI: 10.1002/ps.5336

2018

66. Ramírez-Bustos, I.; López-Martínez, V.; Juarez-Lopez, P.; Alía-Tejacal, I.; Guillén-Sánchez, D.; Saldarriaga-Noreña, H.*; León-Rivera, I. Monitoring of Pesticides in the Cultivation of Nopal Vegetable (Opuntia Ficus-Indica (L.)) Mill, Morelos, México. Agriculture 2018, 8 (11), 174. DOI: 10.3390/agriculture8110174

65. Rios, M. Y.*; Córdova-Albores, L. C.; Ramírez-Cisneros, M. Á.; King-Díaz, B.; Lotina-Hennsen, B.; León Rivera, I.; Miranda-Sánchez, D. Phytotoxic Potential of Zanthoxylum Affine and Its Major Compound Linarin as a Possible Natural Herbicide. ACS Omega 2018, 3 (11), 14779–14787. DOI: 10.1021/acsomega.8b02020

64. Hidalgo-Figueroa, S.*; Estrada-Soto, S.; Ramírez-Espinosa, J. J.; Paoli, P.; Lori, G.; León-Rivera, I.; Navarrete-Vázquez, G.* Synthesis and Evaluation of Thiazolidine-2,4-Dione/Benzazole Derivatives as Inhibitors of Protein Tyrosine Phosphatase 1B (PTP-1B): Antihyperglycemic Activity with Molecular Docking Study. Biomed. Pharmacother. 2018, 107, 1302–1310. DOI: 10.1016/j.biopha.2018.08.124

63. Guevara, P.*; Jorge Reyna-Segura, B. Z.-R.; Enrique, L.-R. R.; F.; A.-Y. M.; B.-G. M.; León-Rivera Ismael, F. E. Biocidal Effect of a Hexane-Soluble Extract of Lippia Graveolens Kunth (Verbenaceae). El Boletín Latinoam. y del Caribe Plantas Med. y Aromáticas 2018, 17, 342–349. Online https://www.blacpma.usach.cl/sites/blacpma/files/articulo_2_-_1465_-_342_-_349.pdf

62. Castro-García, J. M.; León-Rivera, I.; Gutiérrez, M. D. C.* Resin Glycosides Evoke the Gaba Release by Sodium- And/or Calcium-Dependent Mechanism. Biomed. Pharmacother. 2018, 97, 496–502. DOI: 10.1016/j.biopha.2017.10.089

2017

61. Colín-Lozano, B.; León-Rivera, I.; Chan-Bacab, M. J.; Ortega-Morales, B. O.; Moo-Puc, R.; López-Guerrero, V.; Hernández-Núñez, E.; Argüello-Garcia, R.; Scior, T.; Barbosa-Cabrera, E.; Navarrete-Vázquez, G.* Synthesis, in Vitro and in Vivo Giardicidal Activity of Nitrothiazole-NSAID Chimeras Displaying Broad Antiprotozoal Spectrum. Bioorg. Med. Chem. Lett. 2017, 27 (15), 3490–3494. DOI: 10.1016/j.bmcl.2017.05.071

60. Mundo, J.; Villeda-Hernández, J.; Herrera-Ruiz, M.; Gutiérrez, M. del C.; Arellano-García, J.; León-Rivera, I.*; Perea-Arango, I.* Neuropharmacological and Neuroprotective Activities of Some Metabolites Produced by Cell Suspension Culture of Waltheria Americana Linn. Biomed. Pharmacother. 2017, 94, 129–139. DOI: 10.1016/j.biopha.2017.07.061

59. Hidalgo-Figueroa, S.*; Navarrete-Vázquez, G.; Estrada-Soto, S.; Giles-Rivas, D.; Alarcón-Aguilar, F. J.; León-Rivera, I.; Giacoman-Martínez, A.; Miranda Pérez, E.; Almanza-Pérez, J. C.* Discovery of New Dual PPARγ-GPR40 Agonists with Robust Antidiabetic Activity: Design, Synthesis and in Combo Drug Evaluation. Biomed. Pharmacother. 2017, 90, 53–61. DOI: 10.1016/j.biopha.2017.03.033

2016

58. Gómez-Calvario, V.; Garduño-Ramírez, M. L.; León-Rivera, I.; Rios, M. Y.* 1 H and 13 C NMR Data on Natural and Synthetic Capsaicinoids. Magn. Reson. Chem. 2016, 54 (4), 268–290. DOI: 10.1002/mrc.4382

57. Flores-Flores, A.; Hernández-Abreu, O.; Rios, M. Y.; León-Rivera, I.; Aguilar-Guadarrama, B.; Castillo-España, P.; Perea-Arango, I.; Estrada-Soto, S.* Vasorelaxant Mode of Action of Dichloromethane-Soluble Extract from Agastache Mexicana and Its Main Bioactive Compounds. Pharm. Biol. 2016, 1–7. DOI: 10.1080/13880209.2016.1184690

56. León‐Rivera, I.*; Río‐Portilla, F.; Enríquez, R. G.; Rangel‐López, E.; Villeda, J.; Rios, M. Y.; Navarrete‐Vázquez, G.; Hurtado‐Días, I.; Guzmán‐Valdivieso, U.; Núñez‐Urquiza, V. Hepta‐, Hexa‐, Penta‐, Tetra‐, and Trisaccharide Resin Glycosides from Three Species of Ipomoea and Their Antiproliferative Activity on Two Glioma Cell Lines. Magn. Reson. Chem. 2016. DOI: 10.1002/mrc.4476

55. Gómez‐Calvario, V.; Garduño‐Ramírez, M. L.; León‐Rivera, I.; Rios, M. Y. Aims & Scope. 2016. DOI: 10.1002/mrc.4340

2015

54. Pérez-Barrón, G.; Ávila-Acevedo, J. G.; García-Bores, A. M.; Montes, S.; García-Jiménez, S.; León-Rivera, I.; Rubio-Osornio, M.; Monroy-Noyola, A.* Neuroprotective Effect of Buddleja Cordata Methanolic Extract in the 1-Methyl-4-Phenylpyridinium Parkinson’s Disease Rat Model. J. Nat. Med. 2015, 69 (1), 86–93. DOI: 10.1007/s11418-014-0866-4

53. Gómez‐Calvario, V.; Garduño‐Ramírez, M. L.; León‐Rivera, I.; Rios, M. Y.* 1H and 13C NMR Data on Natural and Synthetic Capsaicinoids. Magn. Reson. Chem. 2015. DOI: 10.1002/mrc.4382

52. Mundo, J.; Castillo-Espana, P.; Villafuerte, M. del C. G.; Camacho, C. A.; León-Rivera, I.; Arellano-Garcia, J.; Perea-Arango, I.* Methanolic Extracts from Roots and Cell Suspension Cultures of Waltheria Americana Linn Induce GABA Release in Cerebral Slices of Mouse Brain. African J. Pharm. Pharmacol. 2015, 9 (5), 139–144. DOI: 10.5897/AJPP2014.4115 

2014

51. León-Rivera, I.*; Villeda-Hernández, J.; Campos-Peña, V.; Aguirre-Moreno, A.; Estrada-Soto, S.; Navarrete-Vázquez, G.; Rios, M. Y.; Aguilar-Guadarrama, B.; Castillo-España, P.; Rivera-Leyva, J. C. Evaluation of the Neuroprotective Activity of Stansin 6, a Resin Glycoside from Ipomoea Stans. Bioorg. Med. Chem. Lett. 2014, 24 (15), 3541–3545. DOI: 10.1016/j.bmcl.2014.05.055

50. Navarrete-Vázquez, G.*; Morales-Vilchis, M. G.; Estrada-Soto, S.; Ramírez-Espinosa, J. J.; Hidalgo-Figueroa, S.; Nava-Zuazo, C.; Tlahuext, H.; Leon-Rivera, I.; Medina-Franco, J. L.; López-Vallejo, F. Synthesis of 2-{2-[(Α/β-Naphthalen-1-Ylsulfonyl) Amino]-1, 3-Thiazol-4-Yl} Acetamides with 11β-Hydroxysteroid Dehydrogenase Inhibition and in Combo Antidiabetic Activities. Eur. J. Med. Chem. 2014, 74, 179–186. DOI: 10.1016/j.ejmech.2013.12.042

49. Navarrete-Vázquez, G.*; Torres-Gómez, H.; Hidalgo-Figueroa, S.; Ramírez-Espinosa, J. J.; Estrada-Soto, S.; Medina-Franco, J. L.; León-Rivera, I.; Alarcón-Aguilar, F. J.; Almanza-Pérez, J. C. Synthesis, in Vitro and in Silico Studies of a PPARγ and GLUT-4 Modulator with Hypoglycemic Effect. Bioorg. Med. Chem. Lett. 2014, 24 (18), 4575–4579. DOI: 10.1016/j.bmcl.2014.07.068

48. Hernandez-Marquez, E.; Lagunas-Martinez, A.; Bermudez-Morales, V. H.; Burgete-Garcfa, A. I.; Leon-Rivera, I.; Montiel-Arcos, E.; Garcia-Villa, E.; Gariglio, P.; Ondarza-Vidaurreta, R. N. Inhibitory Activity of Lingzhi or Reishi Medicinal Mushroom, Ganoderma Lucidum (Higher Basidiomycetes) on Transformed Cells by Human Papillomavirus. Int. J. Med. Mushrooms 2014, 16 (2). DOI: 10.1615/IntJMedMushr.v16.i2.80 

47. León-Rivera, I.*; Castro, J. M.; Mirón-López, G.; del Río-Portilla, F.; Enríquez, R. G.; Reynolds, W. F.; Estrada-Soto, S.; Rendón-Vallejo, P.; del Carmen Gutiérrez, M.; Herrera-Ruiz, M. Resin Glycosides from Ipomoea Tyrianthina and Their Sedative and Vasorelaxant Effects. J. Nat. Med. 2014, 68 (4), 655–667. DOI: 10.1007/s11418-014-0844-x

2013

46. López-Martínez, S.; Navarrete-Vázquez, G.; Estrada-Soto, S.; León-Rivera, I.; Rios, M. Y.* Chemical Constituents of the Hemiparasitic Plant Phoradendron Brachystachyum DC Nutt (Viscaceae). Nat. Prod. Res. 2013, 27 (2), 130–136. DOI: 10.1080/14786419.2012.662646

45. Aguirre-Moreno, A.; Campos-Pena, V.; del Rio-Portilla, F.; Herrera-Ruiz, M.; Leon-Rivera, I.; Montiel-Arcos, E.; Rodriguez, V.; Tello, I.; Villeda-Hernandez, J. Anticonvulsant and Neuroprotective Effects of Oligosaccharides from Lingzhi or Reishi Medicinal Mushroom, Ganoderma Lucidum (Higher Basidiomycetes). Int. J. Med. Mushrooms 2013, 15 (6). DOI: 10.1615/IntJMedMushr.v15.i6.40 

2012

44. Ríos, M. Y.; Ramírez-Cisneros, M. Á.; León-Rivera, I.; Estrada-Soto, S.; Navarrete-Vázquez, G.; Aguilar-Guadarrama, A. B.* Complete NMR Assignment of 3, 4-Seco-Lup-20(29)-En-3-Oic Acid from Decatropis Bicolor. Magn. Reson. Chem. 2012, 50 (4), 329–331. DOI: 10.1002/mrc.2875

43. Estrada-Soto, S.*; Gabriel, N.-V.; Léon-Rivera, I.; Rios, M.; Aguilar-Guadarrama, B.; Castillo-España, P.; Ortiz-Andrade, R.; Aguirre-Crespo, F. Antihypertensive Effect of Lepechinia Caulescens Extract on Spontaneously Hypertensive Rats. Phytopharmacology 2012, 2 (1), 170–178. Online: https://www.researchgate.net/profile/Samuel_Estrada-Soto/publication/5932421_Spasmolytic_action_of_Lepechinia_caulescens_is_through_calcium_channel_blockade_and_NO_release/links/00463531dd065bbf96000000.pdf

2011

42. León-Rivera, I.*; Herrera-Ruiz, M.; Estrada-Soto, S.; Gutiérrez, M. del C.; Martínez-Duncker, I.; Navarrete-Vázquez, G.; Rios, M. Y.; Aguilar, B.; Castillo-España, P.; Aguirre-Moreno, A. Sedative, Vasorelaxant, and Cytotoxic Effects of Convolvulin from Ipomoea Tyrianthina. J. Ethnopharmacol. 2011, 135 (2), 434–439. DOI: 10.1016/j.jep.2011.03.041

41. Aguirre Moreno, A. C.; Campos Pena, V.; Villeda Hernandez, J.; Leon Rivera, I.*; Montiel Arcos, E. Ganoderma Lucidum Reduces Kainic Acid-Induced Hippocampal Neuronal Damage via Inflammatory Cytokines and Glial Fibrillary Acid Protein Expression. In Proc West Pharmacol Soc; 2011; Vol. 54, pp 78–79. Online: https://www.researchgate.net/profile/Juana_Villeda-hernandez/publication/221712039_Ganoderma_lucidum_reduces_kainic_acid-induced_hippocampal_neuronal_damage_via_inflammatory_cytokines_and_glial_fibrillary_acid_protein_expression/links/00b7d52e9733fd6f93000000.pdf

40. Romero-Castro, A.*; León-Rivera, I.; Ávila-Rojas, L. C.; Navarrete-Vázquez, G.; Nieto-Rodríguez, A.* Synthesis and Preliminary Evaluation of Selected 2-Aryl-5 (6)-Nitro-1H-Benzimidazole Derivatives as Potential Anticancer Agents. Arch. Pharm. Res. 2011, 34 (2), 181–189. DOI: 10.1007/s12272-011-0201-5

2010

39. Nava-Zuazo, C.; Estrada-Soto, S.; Guerrero-Álvarez, J.; León-Rivera, I.; Molina-Salinas, G. M.; Said-Fernández, S.; Chan-Bacab, M. J.; Cedillo-Rivera, R.; Moo-Puc, R.; Mirón-López, G.; Navarrete Vázquez G.* Design, Synthesis, and in Vitro Antiprotozoal, Antimycobacterial Activities of N-{2-[(7-Chloroquinolin-4-Yl) Amino] Ethyl} Ureas. Bioorg. Med. Chem. 2010, 18 (17), 6398–6403. DOI: 10.1016/j.bmc.2010.07.008

38. Navarrete-Vázquez, G.*; Hidalgo-Figueroa, S.; Torres-Piedra, M.; Vergara-Galicia, J.; Rivera-Leyva, J. C.; Estrada-Soto, S.*; León-Rivera, I.; Aguilar-Guardarrama, B.; Rios-Gómez, Y.; Villalobos-Molina, R. Synthesis, Vasorelaxant Activity and Antihypertensive Effect of Benzo[d]imidazole Derivatives. Bioorg. Med. Chem. 2010, 18 (11), 3985–3991 DOI: 10.1016/j.bmc.2010.04.027

37. Guzmán-Pantoja, L. E.; Guevara-Fefer, P.; Villarreal-Ortega, M. L.; León-Rivera, I.; Aranda-Escobar, E.; Martínez-Peniche, R. Á.; Hernández-Velázquez, V. M.* Biological Activity of Ipomoea Pauciflora Martens and Galeotti (Convolvulaceae) Extracts and Fractions on Larvae of Spodoptera Frugiperda JE Smith (Lepidoptera: Noctuidae). African J. Biotechnol. 2010 9 (24), 3659–3665. DOI: 10.5897/AJB09.1947 

2009

36. Aguilar-Guadarrama, B.; Navarro, V.; León-Rivera, I.; Rios, M. Y.* Active Compounds against Tinea Pedis Dermatophytes from Ageratina Pichinchensis Var. Bustamenta. Nat. Prod. Res. 2009, 23 (16), 1559–1565. DOI: 10.1080/14786410902843301

35. Hernández-Abreu, O.; Castillo-España, P.; León-Rivera, I.; Ibarra-Barajas, M.; Villalobos-Molina, R.; González-Christen, J.; Vergara-Galicia, J.; Estrada-Soto, S.* Antihypertensive and Vasorelaxant Effects of Tilianin Isolated from Agastache Mexicana Are Mediated by NO/cGMP Pathway and Potassium Channel Opening. Biochem. Pharmacol. 2009, 78 (1), 54–61. DOI: 10.1016/j.bcp.2009.03.016

34. Navarrete-Vazquez, G.*; Paoli, P.*; León-Rivera, I.; Villalobos-Molina, R.; Medina-Franco, J. L.; Ortiz-Andrade, R.; Estrada-Soto, S.; Camici, G.; Diaz-Coutiño, D.; Gallardo-Ortiz, I. Synthesis, in Vitro and Computational Studies of Protein Tyrosine Phosphatase 1B Inhibition of a Small Library of 2-Arylsulfonylaminobenzothiazoles with Antihyperglycemic Activity. Bioorg. Med. Chem. 2009, 17 (9), 3332–3341. DOI: 10.1016/j.bmc.2009.03.042

33. León-Rivera, I.*; Mirón-López, G.; Estrada-Soto, S.; Aguirre-Crespo, F.; del Carmen Gutiérrez, M.; Molina-Salinas, G. M.; Hurtado, G.; Navarrete-Vázquez, G.; Montiel, E. Glycolipid Ester-Type Heterodimers from Ipomoea Tyrianthina and Their Pharmacological Activity. Bioorg. Med. Chem. Lett. 2009, 19 (16), 4652–4656. DOI: 10.1016/j.bmcl.2009.06.087

32. Salinas Sánchez, D. O.*; Arteaga Najera, G. L.; León Rivera, I.; Dorado Ramírez, O.; Valladares Cisneros, M.; Navarro García, V. M.* Actividad Antimicrobiana de Las Plantas Medicinales de La Reserva de La Biosfera Sierra de Huautla En Morelos (México). Polibotánica 2009, No. 28, 213–225. Online: http://www.scielo.org.mx/scielo.php?pid=S1405-27682009000200010&script=sci_arttext&tlng=pt

31. Sánchez, D. O. S.*; Najera, G. L. A.; Rivera, I. L.; Dorado, O.; Ramírez, M.; Cisneros, G. V.; García, V. M. N.* Antimicrobial Activity of Medicinal Plants from the Huautla Sierra Biosphere Reserve in Morelos (México). Polibotánica 2009, 28, 213–225. Online: http://scielo.unam.mx/pdf/polib/n28/n28a10.pdf

30. Curzio, L. G. V.*; Velazquez, V. M. H.; Rivera, I. L.; Fcfcr, P. G.; Escobar, E. A. Biological Activity of Mtthanolic Extracts Oïlpomoea Murucvides Roem et Schult on Spodoptera Fmgiperda JE Smith. 2009. Online: http://www.docsdrive.com/pdfs/academicjournals/je/2009/109-116.pdf

29. Abreu Patricia Castillo-España Ismael León-Rivera Maximiliano Ibarra-Barajas Rafael Villalobos-Molina Judith González-Christen Jorge Vergara Galicia- Samuel Estrada-Soto.*- Oswaldo Hernandez A. Antihypertensive and Vasorelaxant Effects of Tilianin Isolated from Agastache Mexicana Are Mediated by NO/cGMP Pathway and Potassium Channel Opening. Biochem. Pharmacol. 2009, No. 1. DOI: 10.1016/j.bcp.2009.03.016

2008

28. León-Rivera, I.*; Mirón-López, G.; Molina-Salinas, G. M.; Herrera-Ruiz, M.; Estrada-Soto, S.; del Carmen Gutiérrez, M.; Alonso-Cortes, D.; Navarrete-Vázquez, G.; Ríos, M. Y.; Said-Fernández, S*. Tyrianthinic Acids from Ipomoea Tyrianthina and Their Antimycobacterial Activity, Cytotoxicity, and Effects on the Central Nervous System. J. Nat. Prod. 2008, 71 (10), 1686–1691. DOI: 10.1021/np800266a

27. Torres-Gómez, H.; Hernández-Núñez, E.; León-Rivera, I.; Guerrero-Alvarez, J.; Cedillo-Rivera, R.; Moo-Puc, R.; Argotte-Ramos, R.; del Carmen Rodríguez-Gutiérrez, M.; Chan-Bacab, M. J.; Navarrete-Vázquez, G.* Design, Synthesis and in Vitro Antiprotozoal Activity of Benzimidazole-Pentamidine Hybrids. Bioorg. Med. Chem. Lett. 2008, 18 (11), 3147–3151. DOI: 10.1016/j.bmcl.2008.05.009

26. Ortiz‐Andrade, R. R.; Sánchez‐Salgado, J. C.; Navarrete‐Vázquez, G.; Webster, S. P.; Binnie, M.; García‐Jiménez, S.; León‐Rivera, I.; Cigarroa‐Vázquez, P.; Villalobos‐Molina, R.; Estrada‐Soto, S.* Antidiabetic and Toxicological Evaluations of Naringenin in Normoglycaemic and NIDDM Rat Models and Its Implications on Extra‐pancreatic Glucose Regulation. Diabetes, Obes. Metab. 2008, 10 (11), 1097–1104. DOI: 10.1111/j.1463-1326.2008.00869.x

25. Moreno-Díaz, H.; Villalobos-Molina, R.*; Ortiz-Andrade, R.; Díaz-Coutiño, D.; Medina-Franco, J. L.; Webster, S. P.; Binnie, M.; Estrada-Soto, S.; Ibarra-Barajas, M.; Navarrete Vázquez G.* Leon-Rivera, I. Antidiabetic Activity of N-(6-Substituted-1, 3-Benzothiazol-2-Yl) Benzenesulfonamides. Bioorg. Med. Chem. Lett. 2008, 18 (9), 2871–2877. DOI: 10.1016/j.bmcl.2008.03.086

2007

24. Navarrete‐Vázquez, G.*; Moreno‐Diaz, H.; Estrada‐Soto, S.; Torres‐Piedra, M.; León‐Rivera, I.; Tlahuext, H.; Muñoz‐Muñiz, O.; Torres‐Gómez, H. Microwave‐Assisted One‐Pot Synthesis of 2‐(Substituted phenyl)‐1 H‐benzimidazole Derivatives. Synth. Commun. 2007, 37 (17), 2815–2825. DOI: 10.1080/00397910701473325

23. Sánchez-Salgado, J. C.; Ortiz-Andrade, R. R.; Aguirre-Crespo, F.; Vergara-Galicia, J.; León-Rivera, I.; Montes, S.; Villalobos-Molina, R.; Estrada-Soto, S.* Hypoglycemic, Vasorelaxant and Hepatoprotective Effects of Cochlospermum Vitifolium (Willd.) Sprengel: A Potential Agent for the Treatment of Metabolic Syndrome. J. Ethnopharmacol. 2007, 109 (3), 400–405. DOI: 10.1016/j.jep.2006.08.008

22. Mirón-López, G.; Herrera-Ruiz, M.; Estrada-Soto, S.; Aguirre-Crespo, F.; Vázquez-Navarrete, L.; León-Rivera, I.* Resin Glycosides from the Roots of Ipomoea Tyrianthina and Their Biological Activity#. J. Nat. Prod. 2007, 70 (4), 557–562. DOI: 10.1021/np0604634

21. Herrera-Ruiz, M.; Gutiérrez, C.; Jiménez-Ferrer, J. E.; Tortoriello, J.; Mirón, G.; León, I.* Central Nervous System Depressant Activity of an Ethyl Acetate Extract from Ipomoea Stans Roots. J. Ethnopharmacol. 2007, 112 (2), 243–247. DOI: 10.1016/j.jep.2007.03.004

20. Kakazey, M.*; Vlasova, M.; Dominguez-Patiño, M.; Leon, I.; Ristic, M. Reactionary Processes during Mechanical Treatment of Mixtures of ZnO and MnO2. I. Formation of Defects and Solid Solution. J. Mater. Sci. 2007, 42 (17), 7116–7122. DOI: 10.1007/s10853-007-1550-9

2006

19. Rios, M. Y.*; Leon, I. Chemical Constituents and Cytotoxic Activity of Smallanthus Maculatus. Chem. Nat. Compd. 2006, 42 (4), 497–498. DOI: 10.1007/s10600-006-0193-4

18. Navarrete-Vázquez, G.*; Moreno-Diaz, H.; Aguirre-Crespo, F.; León-Rivera, I.; Villalobos-Molina, R.; Muñoz-Muñiz, O.; Estrada-Soto, S. Design, Microwave-Assisted Synthesis, and Spasmolytic Activity of 2-(Alkyloxyaryl)-1H-Benzimidazole Derivatives as Constrained Stilbene Bioisosteres. Bioorg. Med. Chem. Lett. 2006, 16 (16), 4169–4173. DOI: 10.1016/j.bmcl.2006.05.082

17. Navarrete-Vazquez, G.*; Estrada-Soto, S.; Villalobos-Molina, R.; Leon-Rivera, I.; Moreno-Diaz, H.; Torres-Piedra, M.; Aguirre-Crespo, F.; Vergara-Galicia, J. MEDI 436-Design, Synthesis and Relaxant Activity of 2-(Substituted Phenyl)-1H-Benzimidazoles on Isolated Rat Aortic Rings. In abstracts of papers of the American Chemical Society; Amer Chemical Soc 1155 16th ST, NW, Washington, DC 20036 USA, 2006; Vol. 232. DOI: 10.1016/j.lfs.2006.01.019

16. Lin, X.*; Murray, J. M.; Rico, A. C.; Wang, M. X.; Chu, D. T.; Zhou, Y.; Del Rosario, M.; Kaufman, S.; Ma, S.; Fang, E. Discovery of 2-Pyrimidyl-5-Amidothiophenes as Potent Inhibitors for AKT: Synthesis and SAR Studies Pp 4163–4168. Bioorg. Med. Chem. Lett. 2006, 16 (16). DOI: 10.1016/j.bmcl.2006.05.092

15. León, I.*; Mirón, G.; Alonso, D. Characterization of Pentasaccharide Glycosides from the Roots of Ipomoea Arborescens. J. Nat. Prod. 2006, 69 (6), 896–902. DOI: 10.1021/np0600604

2005

14. León, I.*; Enríquez, R. G.; Nieto, D. A.; Alonso, D.; Reynolds, W. F.; Aranda, E.; Villa, J. Pentasaccharide Glycosides from the Roots of Ipomoea M Urucoides. J. Nat. Prod. 2005, 68 (8), 1141–1146. DOI: 10.1021/np050075m

2004

13. León, I.*; Enríquez, R. G.; Gnecco, D.; Villarreal, M. L.; Cortés, D. A.; Reynolds, W. F.; Yu, M. Isolation and Characterization of Five New Tetrasaccharide Glycosides from the Roots of Ipomoea S Tans and Their Cytotoxic Activity. J. Nat. Prod. 2004, 67 (9), 1552–1556. DOI: 10.1021/np0400454

2003

12. Rios, M. Y.*; Castrejon, F.; Robledo, N.; Leon, I.; Rojas, G.; Navarro, V. Chemical Composition and Antimicrobial Activity of the Essential Oils from Annona Cherimola (Annonaceae). Rev. la Soc. Química México 2003, 47 (3), 139–142. Online http://www.yolanda-rios.net/papers/WRSQM03139.pdf

2001

11. Godoy-Alcántar, C.; Rivera, I. L.; Yatsimirsky, A. K.* Anion Recognition by Thiostrepton. Bioorg. Med. Chem. Lett. 2001, 11 (5), 651–654. DOI: 10.1016/S0960-894X(01)00025-7

10. Lara, K. O.; Godoy‐Alcántar, C.; Rivera, I. L.; Eliseev, A. V.*; Yatsimirsky, A. K.* Complexation of Dicarboxylates and Phosphates by a Semisynthetic Alkaloid‐based Cyclophane in Water. J. Phys. Org. Chem. 2001, 14 (7), 453–462. DOI: 10.1002/poc.387

1998

9. León, I.; Enríquez, R. G.; McLean, S.; Reynolds, W. F.*; Yu, M. Isolation and Identification by 2D NMR of Two New Complex Saponins from Michrosechium Helleri. Magn. Reson. Chem. 1998, 36 (S1), S111–S117. DOI: 10.1002/(SICI)1097-458X(199806)36:13<S111::AID-OMR307>3.0.CO;2-9

1997

8. Reynolds, W. F.*; Yu, M.; Enriquez, R. G.; Leon, I. Investigation of the Advantages and Limitations of Forward Linear Prediction for Processing 2D Data Sets. Magn. Reson. Chem. 1997, 35 (8), 505–519. DOI: 10.1002/(SICI)1097-458X(199708)35:8<505::AID-OMR130>3.0.CO;2-K

7. Enriquez, R. G.; Barajas, J.; Ortiz, B.; Lough, A. J.; Reynolds, W. F.; Yu, M.; Leon, I.; Gnecco, D. Comparison of Crystal and Solution Structures and 1H and 13C Chemical Shifts for Grandiflorenic Acid, Kaurenoic Acid, and Monoginoic Acid. Can. J. Chem. 1997, 75 (3), 342–347. DOI: 10.1055/s-2006-957976

1996

6. Enríquez, R. G.; Miranda-G, E.; Ortiz, B.; León, I.; Magos, G.; Peña, A.; Reynolds, W. F.; Gnecco, D. The Unambiguous Detection of Kaurenic Derivatives in Aqueous Infusions of Montanoa Tomentosa by GC-MS and 2D-NMR Spectroscopy: An Answer to Contradictory Reports. Planta Med. 1996, 62 (6), 569–571. DOI: 10.1055/s-2006-957976

1995

5. Reynolds, W. F.*; Yu, M.; Enriquez, R. G.*; Gonzalez, H.; Leon, I.; Magos, G.; Villareal, M. L. Isolation and Characterization of Cytotoxic and Antibacterial Tetrasaccharide Glyclosides from Ipomoea Stans. J. Nat. Prod. 1995, 58 (11), 1730–1734. DOI: 10.1021/np50125a014

4. Enriquez, R. G.*; Fernandez-G, J. M.; Leon, I.; Reynolds, W. F.*; Yang, J.-P.; Yu, M. Investigation of the Effect of Ring Size on the Product Distribution for the Schiff Base Reaction of 2-Acetylcycloalkanones with Diamino Alkanes. Can. J. Chem. 1995, 73 (1), 16–21. DOI: 10.1139/v95-004

1992

3. Enriquez, R. G.; Leon, I.; Perez, F.; Walls, F.; Carpenter, K. A.; Puzzuoli, F. V; Reynolds, W. F.* Characterization, by Two-Dimensional NMR Spectroscopy, of a Complex Tetrasaccharide Glycoside Isolated from Ipomoea Stans. Can. J. Chem. 1992, 70 (3), 1000–1008. DOI: 10.1139/v92-132

1987

2. Compadre, C. M.; Hussain, R. A.; Leon, I.; Enríquez, R. G. Volatile Constituents of Montanoa Tomentosa and Lippia Graveolens. Planta Med. 1987, 53 (5), 495–496. DOI: 10.1055/s-2006-962781

1986

1. Reynolds, W. F.*; McLean, S.; Poplawski, J.; Enriquez, R. G.; Escobar, L. I.; Leon, I. Total Assignment of 13 C and 1 H Spectra of Three Isomeric Triterpenol Derivatives by 2D NMR: An Investigation of the Potential Utility of 1 H Chemical Shifts in Structural Investigations of Complex Natural Products. Tetrahedron 1986, 42 (13), 3419–3428. DOI: 10.1016/S0040-4020(01)87309-9



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