PH-Escalante García Jaime
Jaime Escalante García

Doctorado en Química Orgánica, CINVESTAV-IPN (1995)
Profesor: Titular C
SNI: Nivel III
Líneas de Investigación: Química Orgánica
Cuerpo Académico: Química Farmacéutica y Biotecnología
jaime@uaem.mx |Teléfono: +52 777 329 79 97 Ext. 6040
ORCID: 0000-0001-5485-0244| Scopus Author ID: 7003360738| Google Académico 

2017

61. Cabrera-Rivera, F. A.; Hernández-Vázquez, L. G.; Flores-Sánchez, P.; Durán-Galván, M.; Escalante, J.* Solvent- and Catalyst-Free Microwave-Assisted Decarboxylation of Malonic Acid Derivatives. Green Sustain. Chem. 2017, 7 (4), 270–280. DOI: 10.4236/gsc.2017.74021

60. Ortega-Rojas, M.; Rivera-Ramírez, J.; Ávila-Ortiz, C.; Juaristi, E.*; González-Muñoz, F.; Castillo, E.*; Escalante, J.* One-Pot Lipase-Catalyzed Enantioselective Synthesis of (R)-(−)-N-Benzyl-3-(Benzylamino)butanamide: The Effect of Solvent Polarity on Enantioselectivity. Molecules 2017, 22 (12), 2189. DOI: 10.3390/molecules22122189

59. Pérez-Venegas, M.; Reyes-Rangel, G.; Neri, A.; Escalante, J.*; Juaristi, E.* Mechanochemical Enzymatic Resolution of N -Benzylated-β 3 -Amino Esters. Beilstein J. Org. Chem. 2017, 13, 1728–1734. DOI: 10.3762/bjoc.13.167

2016

58. Torres-Huerta, A.; Cruz-Huerta, J.; Höpfl, H.*; Hernández-Vázquez, L. G.; Escalante-García, J.; Jiménez-Sánchez, A.; Santillan, R.; Hernández-Ahuactzi, I. F.; Sánchez, M. Variation of the Molecular Conformation, Shape, and Cavity Size in Dinuclear Metalla-Macrocycles Containing Hetero-Ditopic Dithiocarbamate–Carboxylate Ligands from a Homologous Series of N-Substituted Amino Acids. Inorg. Chem. 2016. DOI: 10.1021/acs.inorgchem.6b02387

57. Rosas-Valdéz, M. E.; Escalante, J.*; Bustos-Jaimes, I.; Regla, I.; Boto, A. Synthesis and Modification of the Amyloid Peptide Sequence 37-42 of Aβ42 (AβPP): Efficient Synthesis of N-Methylated Peptides, Expanding the Tools for Peptide Research. J. Mex. Chem. Soc. 2016, 60 (3), 125–134. Online http://www.redalyc.org/pdf/475/47548008004.pdf

56. Boto, A.; Escalante, J. 1‐(Trimethylsilyl)‐1H‐benzotriazole. e-EROS Encycl. Reagents Org. Synth. DOI: 10.1002/047084289X.rn01189

2015

55. Rangel, H.; Carrillo-Morales, M.; Galindo, J. M.; Castillo, E.; Obregón-Zúñiga, A.; Juaristi, E.; Escalante, J.* Structural Features of N-Benzylated-β-Amino Acid Methyl Esters Essential for Enantiodifferentiation by Lipase B from Candida Antarctica in Hydrolytic Reactions. Tetrahedron: Asymmetry 2015, 26 (7), 325–332. DOI: 10.1016/j.tetasy.2015.02.007

54. Rivera-Ramírez, J. D.; Escalante, J.*; López-Munguía, A.; Marty, A.; Castillo, E.* Thermodynamically Controlled Chemoselectivity in Lipase-Catalyzed Aza-Michael Additions. J. Mol. Catal. B Enzym. 2015, 112, 76–82. DOI: 10.1016/j.molcatb.2014.12.009

2014

53. Cabrera-Rivera, F. A.; Escalante, J.* Synthesis, Resolution and Absolute Configuration of 2, 3-Dihydro-2-Tert-Butyl-3-N-Benzylquinazolin-4-One: A Possible Chiral Auxiliary for Synthesis of β-Amino Cyclohexancarboxylic Acid. Int. J. Org. Chem. 2014, 2014. DOI: 10.4236/ijoc.2014.41007

52. Robledo, N.*; Vega, M.; Escalante, J.; Arzuffi, R. A New Component of the Male Papaya Fruit Fly (Diptera: Tephritidae) Sex Pheromone. Florida Entomol. 2014, 97 (3), 1260–1262. DOI: 10.1653/024.097.0338

51. Del-Oso, J.-A.; Maldonado, J.-L.*; Ramos-Ortíz, G*.; Rodríguez, M.; Güizado-Rodríguez, M.*; Escalante, J.; Frontana-Uribe, B. A.; Pérez-Gutiérrez, E.; Santillan, R. New Polythiophene Derivatives and Enhanced Photovoltaic Effect by a Boron Compound Blended with Them in OPVs Cells. Synth. Met. 2014, 196, 83–91. DOI: 10.1016/j.synthmet.2014.07.019

50. Cabrera-Rivera, F. A.; Escalante, J.*; Morales-Rojas, H.; Zigler, D. F.; Schmidt, R. D.; Jarocha, L. E.; Forbes, M. D. E.* Photophysical Properties of 2, 3-Dihydroquinazolin-4 (1H)-One Derivatives. J. Photochem. Photobiol. A Chem. 2014, 294, 31–37. DOI: 10.1016/j.jphotochem.2014.07.005

2012

49. Cervantes Cuevas, H.*; García Martínez, C.; Escalante García, J. Reacción de N, N’-bis (2-Heteroaril) Etilendiaminas Con Aldehídos, Nuevas Imidazolidinas. Rev. Latinoam. química 2012, 40 (3), 187–198. Online http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0370-59432012000300009

48. Navarrete-Vazquez.*;  Ramírez-Martínez, M., Estrada-Soto, S., Nava-Zuazo, C., Paoli, P., Camici, G., Escalante-García, J., (...), Ortiz-Andrade, R., G. Synthesis, in Vitro and in Silico Screening of Ethyl 2-(6-Substituted Benzo[d]thiazol-2-Ylamino)-2-Oxoacetates as Protein-Tyrosine Phosphatase 1B Inhibitors. Eur. J. Med. Chem. 2012, 53, 346–355. DOI: 10.1016/j.ejmech.2012.04.025

47. Hernández‐Vázquez, L. G.; Leyva, M. A.; Metta‐Magaña, A. J.; Escalante, J.* Microwave‐Assisted Synthesis of β‐Lactams and Cyclo‐β‐dipeptides. Helv. Chim. Acta 2012, 95 (11), 2218–2230. DOI: 10.1002/hlca.201200449

46. Cabrera-Rivera, F. A.; Ortíz-Nava, C.; Escalante, J.*; Hernández-Pérez, J. M.; Hô, M. Photoinduced Elimination in 2, 3-Dihydro-2-Tert-Butyl-3-Benzyl-4 (1H)-Quinazolinone: Theoretical Calculations and Radical Trapping Using TEMPO Derivatives. Synlett 2012, 23 (7), 1057–1063. DOI: 10.1055/s-0031-1290492

45. Sandoval-González, A.; Borja-Arco, E.; Escalante, J.; Jiménez-Sandoval, O.; Gamboa, S. A.* Methanol Oxidation Reaction on PtSnO 2 Obtained by Microwave-Assisted Chemical Reduction. Int. J. Hydrogen Energy 2012, 37 (2), 1752–1759. DOI: 10.1016/j.ijhydene.2011.10.049

44. Cabrera-Rivera, F. A.; Ortíz-Nava, C.; Román-Bravo, P.; Leyva, M. A.; Escalante, J.* Direct Halogenation Reactions in 2, 3-Dihydro-4 (1H)-Quinazolinones. Heterocycles 2012, 85 (9), 2173. DOI: 10.3987/COM-12-12473

2011

43. Borja-Arco, E.*; Jiménez-Sandoval, O.; Escalante-García, J.; Magallón-Cacho, L.; Sebastian, P. J.* Microwave Assisted Synthesis of Osmium Electrocatalysts for the Oxygen Reduction Reaction in the Absence and Presence of Aqueous Methanol. Int. J. Electrochem. 2011, 2011. DOI: 10.4061/2011/830541

42. Borja-Arco, E.; Sandoval, O. J.; Escalante-García, J.; Sandoval-González, A.; Sebastian, P. J.* Microwave Assisted Synthesis of Ruthenium Electrocatalysts for Oxygen Reduction Reaction in the Presence and Absence of Aqueous Methanol. Int. J. Hydrogen Energy 2011, 36 (1), 103–110. DOI: 10.1016/j.ijhydene.2010.10.051

41. Garcia-Martinez, C.*; Cervantes, H.; Mendez, F.; Escalante, J. Stoichiometry, Association Constant, and Solvation Model of Chiral Hydroxyfuranones in the Presence of Pirkle’s Alcohols. Spectrosc. Lett. 2011, 44 (3), 168–175. DOI: 10.1080/00387010.2010.489096

40. Nicho, M. E.*; Medrano-Baca, M. G.; León-Silva, U.; Escalante, J.; González-Rodríguez, G.; Güizado-Rodríguez, M.; Linzaga-Elizalde, I. Effect of Adhesion Promoter in Corrosion Protection of 1018 Mild Steel by Using Poly (3-Hexylthiophene) Coatings in 0.5 M H2SO4 Solution. Corros. J. Sci. Eng. 2011, 67 (10), 105002. DOI: 10.5006/1.3647763

2010

39. Güizado-Rodríguez, M.*; López-Tejeda, M.; Escalante, J.; Guerrero-Álvarez, J. A.; Nicho, M. E. Photosensitive Polyaniline Colloidal Particles Prepared by Enzymatic Polymerization Using the Azopolymer DMA-Co-AZAAm as Stabilizer. Mater. Chem. Phys. 2010, 124 (1), 389–394. DOI: 10.1016/j.matchemphys.2010.06.052

38. Miranda-Molina, A.; López-Munguía, A.; San Román, M. L.; Escalante, J.; Leyva, M. A.; Puebla, A. M.; Castillo, E.*; Álvarez, L.* Stereoselective Enzymatic Synthesis of Monoglucosyl-Myo-Inositols with in Vivo Anti-Inflammatory Activity. Tetrahedron: Asymmetry 2010, 21 (1), 43–50. DOI: 10.1016/j.tetasy.2009.12.009
2009

37. Robledo, N.; Escalante, J.*; Arzuffi, R. Extraction with SPME and Synthesis of 2-Methyl-6-Vinylpyrazine by a “One Pot”reaction Using Microwaves. Molecules 2009, 14 (6), 2160–2166. DOI: 10.3390/molecules14062160

36. Díaz-Coutiño, F. D.; Escalante, J.* Efficient ’One Pot’ Nitro Reduction-Protection of γ-Nitro Aliphatic Methyl Esters. J. Mex. Chem. Soc. 2009, 53 (3), 93–95. Online http://www.scielo.org.mx/pdf/jmcs/v53n3/v53n3a3.pdf

35. Escalante, J.*; Díaz-Coutiño, F. D. Synthesis of γ-Nitro Aliphatic Methyl Esters via Michael Additions Promoted by Microwave Irradiation. Molecules 2009, 14 (4), 1595–1604. DOI: 10.3390/molecules14041595

34. Priego, J.; Ortíz-Nava, C.; Carrillo-Morales, M.; López-Munguía, A.; Escalante, J.*; Castillo, E.* Solvent Engineering: An Effective Tool to Direct Chemoselectivity in a Lipase-Catalyzed Michael Addition. Tetrahedron 2009, 65 (2), 536–539. DOI: 10.1016/j.tet.2008.10.103

33. Linzaga-Elizalde, I.*; Escalante, J.; Nicho, M. E.; Güizado-Rodríguez, M. Synthesis of 2-(Thiophen-3-Yl) Vinylphosphonic Acid. Synth. Commun. 2009, 39 (9), 1511–1515. DOI: 10.1080/00397910902784462

32. Marquina, S.; Parra, J. L.; González, M.; Zamilpa, A.; Escalante, J.; Trejo-Hernández, M. R.; Álvarez, L.* Hydroxylation of the Diterpenes Ent-Kaur-16-En-19-Oic and Ent-Beyer-15-En-19-Oic Acids by the Fungus Aspergillus Niger. Phytochemistry 2009, 70 (17), 2017–2022. DOI: 10.1016/j.phytochem.2009.09.005

31. Pérez-Picaso, L.; Escalante, J.; Olivo, H. F.; Rios, M. Y.* Efficient Microwave Assisted Syntheses of 2,5-Diketopiperazines in Aqueous Media. Molecules 2009, 14 (8), 2836–2849. DOI: 10.3390/molecules14082836

2008

30. Escalante, J. Enzymatic Resolution of β‐Amino Methyl Esters Using Lipase B from Candida Antarctica. In recent developments in physical chemistry: third mexican meeting on mathematical and experimental physics; AIP Publishing, 2008; Vol. 979, pp 60–67. DOI:10.1063/1.2901848

29. Escalante, J.*; Carrillo-Morales, M.; Linzaga, I. Michael Additions of Amines to Methyl Acrylates Promoted by Microwave Irradiation. Molecules 2008, 13 (2), 340–347. DOI: 10.3390/molecules13020340

28. Cruz-Huerta, J.; Carillo-Morales, M.; Santacruz-Juárez, E.; Hernández-Ahuactzi, I. F.; Escalante-García, J.; Godoy-Alcantar, C.; Guerrero-Alvarez, J. A.; Höpfl, H.*; Morales-Rojas, H.; Sánchez, M. Macrocyclic Diorganotin Complexes of γ-Amino Acid Dithiocarbamates as Hosts for Ion-Pair Recognition. Inorg. Chem. 2008, 47 (21), 9874–9885. DOI: 10.1021/ic8007987

2007

27. Escalante, J.*; Ortíz-Nava, C.; Flores, P.; Priego, J. M.; García-Martínez, C.* Synthesis, NMR and Crystallographic Studies of 2-Substituted Dihydroquinazolinones Derived from (S)-Phenylethylamine. Molecules 2007, 12 (2), 173–182. DOI: 10.3390/12020173

26. Torres-Gavilán, A.; Escalante, J.; Regla, I.; López-Munguía, A.; Castillo, E.* “Easy-On, Easy-Off”resolution of Chiral 1-Phenylethylamine Catalyzed by Candida Antarctica Lipase B. Tetrahedron: Asymmetry 2007, 18 (22), 2621–2624. DOI: 10.1016/j.tetasy.2007.10.045

2006

25. García-Martínez, C.*; Pérez-Espino, M. A.; Cervantes-Cuevasl, I. H.; Escalante-García, J. Synthesis of mB—Epoxysulfoxides: Thermodynamic Control in Base—induced Cyclization of Chlorohydrins Derived from a—Chlorobenzyl Phenyl Sulfoxide and Alkyl Aldehydes. 2006. Online http://www.scielo.org.mx/scielo.php?pid=S1870-249X2006000300013&script=sci_arttext

24. Campo, M. A.; Escalante, J.; Sebesta, R. β 2-Amino Acids with Proteinogenic Side Chains and Corresponding Peptides: Synthesis, Secondary Structure, and Biological Activity. EnantioselectiVe Synth. β-Amino Acids 2006, 593–617. DOI: 10.1002/0471698482.ch23 

23. González‐Juárez, E.; Ortega‐Guevara, A.; Linzaga‐Elizalde, I.*; Escalante, J. NMR and X‐ray Crystallographic Studies of Linear and Cyclic Aminomethanephosphinates. Heteroat. Chem. 2006, 17 (2), 81–87. DOI: 10.1002/hc.20179

2005

22. Arvidsson, P. I.; Ryder, N. S.; Weiss, H. M.; Hook, D. F.; Escalante, J.; Seebach, D.* Exploring the Antibacterial and Hemolytic Activity of Shorter-and Longer-Chain B-, A, B-, and G-Peptides, and of B-Peptides from β2 -3-Aza-and b3-2-Methylidene-Amino Acids Bearing Proteinogenic Side Chains-A Survey. Chem. Biodivers. 2005, 2, 401. DOI: 10.1002/cbdv.200590020

21. Flores-Sánchez, P.; Escalante, J.*; Castillo, E. Enzymatic Resolution of N-Protected-β 3-Amino Methyl Esters, Using Lipase B from Candida Antarctica. Tetrahedron: Asymmetry 2005, 16 (3), 629–634. DOI: 10.1016/j.tetasy.2004.11.082

2004

20. Bivián-Castro, E. Y.; Bernes, S.; Escalante, J.; Mendoza-Díaz, G. Chloro (histamine)(1, 10-Phenanthroline) Copper (II) Chloride Monohydrate. Acta Crystallogr. Sect. C Cryst. Struct. Commun. 2004, 60 (5), m205–m207. DOI: 10.1107/S0108270104006560

19. Melgar-Fernandez, R.; Demare, P.; Hong, E.; Rosas, M. A.; Escalante, J.; Munoz-Muniz, O.; Juaristi, E.; Regla, I.* Synthesis and Cardiovascular Activity of Metoprolol Analogues. Bioorg. Med. Chem. Lett. 2004, 14 (1), 191–194. DOI: 10.1016/j.bmcl.2003.09.070

18. Escalante, J.; Flores, P.; Priego, J. M. Synthesis of 2, 3-Dihydro-4 (1H)-Quinazollnones. Heterocycles-Sendai Inst. Heterocycl. Chem. 2004, 63 (9), 2019–2032. 

17. Priego, J.; Flores, P.; Ortiz-Nava, C.; Escalante, J.* Synthesis of Enantiopure Cis-and Trans-2-Aminocyclohexane-1-Carboxylic Acids from Octahydroquinazolin-4-Ones. Tetrahedron: Asymmetry 2004, 15 (22), 3545–3549. DOI: 10.1016/j.tetasy.2004.08.032
16. Nicho, M. E.*; Hu, H.; López-Mata, C.; Escalante, J. Synthesis of Derivatives of Polythiophene and Their Application in an Electrochromic Device. Sol. Energy Mater. Sol. Cells 2004, 82 (1), 105–118. DOI: 10.1016/j.solmat.2004.01.009

2003

15. García‐Martínez, C.*; Cervantes‐Cuevas, H.; Escalante‐Garcia, J. Synthesis and NMR Configurational Analysis of 1, 3‐imidazolidin‐4‐ones Derived from (−)‐(S)‐phenylethylamine. Chirality 2003, 15 (S1), S74–S81. DOI: 10.1002/chir.10280

14. Escalante, J.*; González-Tototzin, M. A. Synthesis, Resolution and Absolute Configuration of Trans 4, 5-Diphenyl-Pyrrolidin-2-One: A Possible Chiral Auxiliary. Tetrahedron: Asymmetry 2003, 14 (8), 981–985. DOI: 10.1016/S0957-4166(03)00097-1

2002

13. Linzaga, I.; Escalante, J.; Muñoz, M.; Juaristi, E.* NMR and X-Ray Crystallographic Studies of Axial and Equatorial 2-Ethoxy-2-Oxo-1, 4, 2-Oxazaphosphinane. Tetrahedron 2002, 58 (44), 8973–8978. DOI: 10.1016/S0040-4020(02)01152-3

2001

12. Escalante, J.*; Hernández, A. L.; Juaristi, E.* Highly Diastereoselective Addition of a Racemic β-Alanine Enolate Derivative to Electrophiles. Rev. la Soc. 2001, 149 (4), 177–182. Online http://www.redalyc.org/pdf/475/47545409.pdf

11. Escalante, J.*; González-Tototzin, M. A.; Aviña, J.; Muñoz-Muñiz, O.; Juaristi, E*. Synthesis of β-Lactams and Cyclo-β-Dipeptides from β-Amino Acids: Experimental Observations and Theoretical Analysis. Tetrahedron 2001, 57 (10), 1883–1890. DOI: 10.1016/S0040-4020(00)01169-8

1999

10. Ramírez-Quirós, Y.; Balderas, M.; Escalante, J.; Quintana, D.; Gallardo, I.; Madrigal, D.; Molins, E.; Juaristi, E.* X-Ray Crystallographic Study of Substituted Perhydropyrimidinones. Extreme Changes in Ring Conformation. J. Org. Chem. 1999, 64 (23), 8668–8680. DOI: 10.1021/jo991297q

9. Juaristi, E.*; León-Romo, J. L.; Reyes, A.; Escalante, J. Recent Applications of α-Phenylethylamine (α-PEA) in the Preparation of Enantiopure Compounds. Part 3: α-PEA as Chiral Auxiliary. Part 4: α-PEA as Chiral Reagent in the Stereodifferentiation of Prochiral Substrates. Tetrahedron: Asymmetry 1999, 10 (13), 2441–2495. DOI: 10.1016/S0957-4166(99)00242-6

1998

8. Juaristi, E.*; López-Ruiz, H.; Madrigal, D.; Ramírez-Quirós, Y.; Escalante, J. α-Alkylation of (S)-Asparagine with Self-Regeneration of the Stereogenic Center: Enantioselective Synthesis of α-Substituted Aspartic Acids1, 2. J. Org. Chem. 1998, 63 (14), 4706–4710. DOI: 10.1021/jo980367a

7. Juaristi, E.*; Escalante, J.; León-Romo, J. L.; Reyes, A. Recent Applications of α-Phenylethylamine (α-PEA) in the Preparation of Enantiopure Compounds. Part 1: Incorporation in Chiral Catalysts. Part 2: α-PEA and Derivatives as Resolving Agents. Tetrahedron: Asymmetry 1998, 9 (5), 715–740. DOI: 10.1016/S0957-4166(98)00058-5

1997

6. Crich, D.*; Escalante, J.; Jiao, X.-Y. Solvent Effects in the β-(Phosphatoxy) Alkyl Radical Migration Asrevealed by Deuterium Labelling and 1H NMR Spectroscopy. J. Chem. Soc., Perkin Trans. 2 1997, No. 3, 627–630. DOI: 10.1039/A603916B

1995

5. Escalante, J.; Juaristi, E.* Enantioselective Synthesis of β-Amino Acids. 6. High 1, 2-Stereoinduction in the Preparation of Enantiopure 2 (R)-Hydroxy-3 (R)-N-Benzoylamino-3-Phenylpropionic Acid (like Stereoisomer of Taxol’s Side Chain). Tetrahedron Lett. 1995, 36 (25), 4397–4400. DOI: 10.1016/0040-4039(95)00859-B

1993

4. Juaristi, E.*; Escalante, J. Enantioselective Synthesis Of. Beta.-Amino Acids. 4. 1, 2 Asymmetric Induction in the Alkylation of 1-Benzoyl-3, 6 (S)-Dimethylperhydropyrimidin-4-One. Preparation of the like and Unlike Stereoisomers of 2-Methyl-and 2-Benzyl-3 (S)-Aminobutanoic Acid. J. Org. Chem. 1993, 58 (8), 2282–2285. DOI: 10.1021/jo00060a051

1992

3. Juaristi, E.*; Escalante, J.; Lamatsch, B.; Seebach, D. Enantioselective Synthesis Of. Beta.-Amino Acids. 2. Preparation of the like Stereoisomers of 2-Methyl-and 2-Benzyl-3-Aminobutanoic Acid. J. Org. Chem. 1992, 57 (8), 2396–2398. DOI: 10.1021/jo00034a037

2. Seebach, D.; Amatsch, B.; Amstutz, R.; Beck, A. K.; Doler, M.; Egli, M.; Fitzi, R.; Gautschi, M.; Herradön, B.; Hidber, P. C. Structure and Reactivity of Five‐and Six‐Ring N, N‐, N, O‐, and O, O‐acetals: A Lesson in Allylic 1, 3‐strain (A1, 3 Strain). Helv. Chim. Acta 1992, 75 (3), 913–934. DOI: 10.1002/hlca.19920750326

1991

1. Juaristi, E.*; Rizo, B.; Natal, V.; Escalante, J.; Regla, I. Alternative Method for the Resolution of 1-Benzoyl-2-Tert-Butyl-3-Methyl-1, 3-Imidazolidin-4-One. Tetrahedron: Asymmetry 1991, 2 (8), 821–826. DOI: 10.1016/S0957-4166(00)80465-6


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